The goal is to study gender features of rheological properties of blood in patients with chronic generalized periodontitis (CGP) from mild to moderate severity. Material and Methods. 80 patients (43.8% male) with CGP aged 42±5 years have been studied. 41 patients (43.9% male) experienced mild severity of CGP, and 39 patients (43.6% male) experienced moderate severity. 40 healthy adults (50% male), aged 31±7 years, have been included into the study. Plasma viscosity on shear rate values 300 sec1 to 5 sec1, and rheological features of erythrocytes (aggregation and deformation) have been evaluated. Results. In healthy women and women with mild severity of CGP, plasma viscosity was lower than in the similar group of men. The rheological features of erythrocytes have not gender differences among healthy adults and patients with mild CGP. Increased severity of CGP has been associated with increased plasma viscosity and rheological features of erythrocytes, particularly in men. Conclusion. Plasma viscosity differs in men and women (childbearing age) (healthy subjects and patients with CGP). In women, severity of pathological changes of plasma viscosity and rheological features of erythrocytes have been determined to be lower than in men.
Kazantsev A.V., Suyetenkov D.Ye., /Andronoy E.V./, J Firsova I.V. Gender features of rheological properties of blood (plasma viscosity, aggregation and deformation of erythrocytes) in patients with chronic generalized periodontitis // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 1, 2014, pp. 56-61

Objective: to establish the relationship of chronic generalized periodontitis, multiple cavities and dentofacial anomalies with various forms of coronary heart disease and its complications. Material and methods. The study included 294 patients with coronary heart disease and its complications. The patients were divided into two groups. Group I included 89 patients with acute Q-myocardial infarction, which was placed in the presence of at least 2 of the following criteria identified on the basis of a comprehensive clinical and instrumental examination: clinical, laboratory confirmation (CK-MB), electrocardiographic signs of damage or myocardial necrosis. The following statistical methods were used: multi-variate and univariate analysis of variance, non-parametric tests, crosstabulation, chi-square test, Fisher»s exact test. As a measure of variability of the normal distribution standard deviation was used. Results. It is noted that in patients with myocardial infarction more likely than in patients without coronary heart attack in history severe generalized periodontitis, dentofacial anomalies and multiple dental caries have appeared. In patients with acute myocardial infarction, severe periodontal disease has been associated with increased fibrinogen levels in the blood and an increase in the dispersion of the interval QT, which are known to be indicators of poor prognosis in acute coronary disease.
Ivaschenko Y.Y., Shvarts Y.G., Parkhonyuk E.V., Eremin O.V. Chronic oral pathology and ischemic heart disease and its complications // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 408-412

Pathogenesis of oral hygiene, smoking, gestosis, immunosuppression and cytokine disbalance affect inflammatory periodontal diseases in pregnant women. The research goal is to study clinical and immunological features of parodentium and cytokine profile in oral cavity of pregnant women. Material and methods: The condition of parodentium tissues was studied at 240 women with physiological pregnancy and 360 with pregnancy complicadet by gestosis. Re-sults: Freguency and character of inflammatory periodontal diseases in pregnancy were defined. Immune and cytokine disbalance contributed greatly to pathogenesis of inflammatory periodontal diseases at pregnant women. Conclusion: Violations of immune homeostasis at the pregnancy, complicated gestosis, authentically are more expressed that contributes to the development of gingivitis and periodontal disease. The imbalance of cytokines can serve in oral liquid as additional diagnostic and predictive marker of severity of a course of inflammatory periodontal disease.
Dubrovskaya M.V., Eremin O.V., Savina Е.А., Ivashchenko Y.Y., Minasyn A.M. Risk factors of development of inflammatory diseases of parodentium in pregnant women // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 383-386