Purpose: the analysis of anthropometric characteristics of cardiovascular continuum of patients with coronary heart disease (CHD). Materials and methods. The study of the leading anthropometric predictors in the long-term prognosis of patients with coronary artery disease is based on the results of observation of 238 patients of both sexes of working age who are undergoing treatment for coronary heart disease in hospitals of Saratov. Anthropometric parameters included in the study of respondents with coronary artery disease, were measured by the common method of V. V. Bu-nak. The received data were processed by standard methods of mathematical statistics. Results. During the research of anthropometric characteristics of respondents with CHD, male, it was found that the average length of the patient's body up to 50 years is of 175,0±1,2cm, aged 51-55 years, is 172,0±0,7cm, age 55 is 175,0±0,9cm. In the process of study it is found that the dynamics of clinical, instrumental and anthropometric indicators for the period of observation is of the predictive value. Conclusion. The analysis of anthropometric predictors, including morphological characteristics and the human body type make it possible to objectify distant prognosis of patients with coronary artery disease.
Baleva E.S., Aleshkina O.Yu., Krom I.L. Anthropometric predictors of cardiovascular continuum in patients with ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 4, 2015, pp. 520-523

The purpose of the study was to estimate clinical signs and course of coronary heart disease in long-livers and centenarians. Material and Methods. The study included overall population of Saratov — Engels agglomeration's long-livers (>=90 years old, n=198). Results. The rates of major clinical forms of coronary heart disease were detected: atrial fibrillation — 10.6%, chronic heart failure (with preserved ejection fraction) — 10.1 % and angina — 5.1 %. Myocardial infarction was verified in 9.6% of long-livers. Myocardial scar criteria prevailed over myocardial infarction history. Received data corroborated dissolving phenomena of coronary heart disease and noninsulin dependent diabetes mellitus in long-livers. Gender differences in electrophysiological parameters were detected in long-livers. Centenarians with the history of myocardial infarction preserved a satisfactory level of physical activity. Conclusion. Received data confirm a presence of an excessive security: prevention of coronary heart disease manifestation and progression in longevity. Long-livers should be considered as a natural model of an antiatherogenic factors and mechanisms.
Markova T.Yu., Malinova L.I., Denisova Т.Р. Heart ischemic disease and longevity: unsolved problems // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 1, 2015, pp. 37-41

Objective: to establish the relationship of chronic generalized periodontitis, multiple cavities and dentofacial anomalies with various forms of coronary heart disease and its complications. Material and methods. The study included 294 patients with coronary heart disease and its complications. The patients were divided into two groups. Group I included 89 patients with acute Q-myocardial infarction, which was placed in the presence of at least 2 of the following criteria identified on the basis of a comprehensive clinical and instrumental examination: clinical, laboratory confirmation (CK-MB), electrocardiographic signs of damage or myocardial necrosis. The following statistical methods were used: multi-variate and univariate analysis of variance, non-parametric tests, crosstabulation, chi-square test, Fisher»s exact test. As a measure of variability of the normal distribution standard deviation was used. Results. It is noted that in patients with myocardial infarction more likely than in patients without coronary heart attack in history severe generalized periodontitis, dentofacial anomalies and multiple dental caries have appeared. In patients with acute myocardial infarction, severe periodontal disease has been associated with increased fibrinogen levels in the blood and an increase in the dispersion of the interval QT, which are known to be indicators of poor prognosis in acute coronary disease.
Ivaschenko Y.Y., Shvarts Y.G., Parkhonyuk E.V., Eremin O.V. Chronic oral pathology and ischemic heart disease and its complications // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 408-412

The review of literature is devoted to the comparative analysis of clinical researches of efficiency and frequency of complications after application of surgical and medicamentous methods of treatment of coronary heart disease.
Sinkeev M.S., Skvortsov Yu.l., Mikhailenko О.A. Comparative analysis of myocardial revascularization methods for ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 3, 2012, pp. 756-764

Purpose: to study the morphological characteristic of a coronary blood flow and feature of erythronJs system at ischemic heart disease in aged patients. Methods. Morphological and functional characteristics of coronary blood flow (according to the data of selective direct angiocoronarography) and also cytomorphological and functional parameters of peripheral blood flow in aged patients with ischemic heart disease have been used. Results. Statistically reliable differences to parameters of «red» blood are determined. Lowering of erythrocytes has been established in women. The parameters of haemoglobin level, hematocrit and increasing of erythrocyte sedimentation rate was marked in both gender. The gender distinctions of age have been revealed remodeling of coronary arteries. Conclusion. The high probability of erythronJs system participation has been shown namely its peripheral link in process of age remodeling of coronary arteries in aged men with ischemic heart disease
Malinova L.I., Akhmadullina L.G. Morphological characteristics of coronary blood flow and eryithron system in elderly patients with ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 2, 2012, pp. 228-232

The article presents the research results on the role of leading clinical predictors in follow-up prognosis for patients with ischemic heart disease. The inefficiency of socialization in a non-terminal condition is formed by means of insufficiency of somatic, psychological and social resources in patients. Thus clinical predictors have no significant value
Osipov D.A., Rozhdestvenskaya T.V., Krom I.L., Rebrov A.P. Correlation of predictors of life quality prognosis of patients with coronary heart disease // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 2, 2011, pp. 426-429

The aim of the research is a comparative investigation of Ivabradin vs Verapamil SR of antianginal/antiischemic activity, physical exertion tolerance and life quality of patients with coronary heart disease (CHD) accompanied by bronchial obstructive diseases. Parallel groups of patients have been examined for a 16-week period. Ivabradin (average dose — 14mg/day) or Verapamil SR (average dose — 443mg/day) were administered to ischemic patients (n=84) with postinfarction cardiosclerosis, stable angina (class l-ll) and painless myocardial ischemia. Concomitant bronchial obstructive deseases included controlled/partly controlled bronchial asthma or chronic obstructive pulmonary disease (stage II-III). Both medications have demonstrated the same antianginal/antiischemic activity and have improved physical exertion tolerance. Ivabradin was more effective for heart rate (HR) aim level and 24-hour HR control. Ivabradin advantages were more expressed by changing of NYHA class (from class II to class I) and increase of 6MWD. In conclusion Ivabradin has demonstrated its effectiveness in life quality improvement. Ivabradin and Verapamil SR did not cause complications in concomitant asthma/COPD and were good tolerated. It was determined that Ivabradin is a good Verapamil SR alternative for CHD treatment in case of bronchial obstructive concomitant diseases
Petrov V.I., Magnitskaya O.V., Likhodeeva Yu.V., Malakhov A.I. Ivabradin and Verapamil Sr efficacy in treatment of coronary heart disease accompanied by bronchial obstructive diseases // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 2, 2011, pp. 410-415

The characteristics of heart remodeling in patients with chronic obstructive pulmonary diseases ( COPD), associated with coronary heart diseases (CHD) were examined. The changes of structural and functional state of myocardium, intracardiac relationships with associated pathology were under study. The role of blood inflammatory cytokines (IL-6, IL-8, TNF-a) and the level of cell adhesion molecules (ICAM-1, VCAM-1) in exacerbating myocardial dysfunction was clarified.
T.G. Shapovalova, N.V.Shelobanova, M.V. Volkova, A.Yu. Ryabova, L.I. Lekareva Features of The Heart Remodeling in Patients with Chronic Obstructive Pulmonary Diseases, Combined with Coronary Heart Diseases // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 3, 2009, pp. 352-355