Research Objective: Evaluate the indicators of mineral metabolism in HIV-infected patients, patients with chronic hepatitis С and co-infection HIV/HCV. Material and Methods: The content of microelements (zinc (Zn), copper (Cu), iron (Fe)) in serum was determined by atomic absorption spectrophotometry. The study involved 99 patients: with chronic hepatitis С — 32 patients, with HIV infection — 34 and co-infection of HIV/HCV — 33 patients. Results: Microelements and metal-dependent proteins metabolic disorders as a reduction of the zinc, haptoglobin contents, and an increase of copper, iron, and ceruloplasmin contents were identified in patients with chronic hepatitis С In HIV-infected patients and patients with co-infection HIV/HCV were identified reducing zinc, copper, iron, haptoglobin, ceruloplasmin. in patients with co-infection HIV/HCV compared HIV-infected patients lower zinc, haptoglobin, ceruloplasmin contents (p<0,001) were detected. In patients with co-infected HIV/HCV, as compared with a group of chronic hepatitis С were set lower values of all parameters (p<0,001). Conclusion: Integrated assessment of the degree of deviation from the control of the trace element content and activity metal-dependent enzymes showed that its highest significance was typical for patients with co-infected HIV/HCV, which is higher than that of HIV-infected patients in the 1,2-fold and 2,2-fold in patients with chronic hepatitis С
Yurko Е.М. Assesment of mineral metabolism in patients with HIV-infection, chronic hepatitis с and co-infection HIV/ chronic hepatitis С // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 4, 2014, pp. 617-622

http://scipeople.ru/publication/120009/; В этой публикации дан анализ недавно вышедшей книги под названием «Инновационные аспекты биогеохимии» В.В. Ермакова, Е.А. Карповой, В.Д. Корж, С.А. Остроумова (г. Москва). В книге изложено большое количество новых фактов из области геохимии, биологии, экологии, биохимии и химии биосферы, подведены итоги исследований авторов в этих областях. Авторы книги изложили также новые полезные идеи по биогеохимии наземных и водных экосистем. Книга рекомендована ученым и преподавателям в области экологических наук, наук о жизни, океанологии, почвоведения и геохимии. Аннотация опубликована онлайн также здесь: https://www.researchgate.net/publication/274254737; СПИСОК ЦИТИРУЕМОЙ ЛИТЕРАТУРЫ: 1. Ермаков В.В., Карпова Е.А., Корж В.Д., Остроумов С.А. Инновационные аспекты биогеохимии/Отв. ред. М.А. Федонкин, С.А. Остроумов. М.: ГЕОХИ РАН, 2012. 340 с. 2. Вернадский В.И. Биосфера. I-II. Л.: Науч. хим.-техн. изд-во, 1926. 147 с. ... 23. Остроумов С.А. Химико-биотические взаимодействия и новое в учении о биосфере В.И. Вернадского. М.: МАКС-пресс, 2013. 92 с. 24. Остроумов С.А. Система принципов для сохранения биогеоценотической функции и биоразнообразия фильтраторов//Доклады Академии наук. 2002. Т. 383.№ 5. С. 710-713. 25. Ostroumov S.A., Widdows J. Inhibition of mussel suspension feeding by surfactants of three classes//Hydrobiologia. 2006. Т. 556. № 1. С. 381-386. 26. Ostroumov S.A. Criteria of ecological hazards due to anthropogenic effects on the biota: searching for a system//Doklady Biological Sciences. 2000. Vol. 371. С. 204-206. 27. Ostroumov S.A. Problems of assessment of biological activity of xenobiotics//Moscow University Biological Sciences Bulletin. 1990. Vоl. 45. № 2. P. 26-32. 28. Ostroumov S.A. Ecological concepts "ecosystem", "biogeocenosis", "ecosystem boundaries": search for new definitions//Moscow University Biological Sciences Bulletin. 2003. Vol. 58. № 3. P. 29-38. 29. Ostroumov S.A. Elements of the qualitative theory of biotic self-purification of aquatic ecosystems. Application of the theory to biodiversity conservation practice//Moscow University Biological Sciences Bulletin. 2004. Vol. 59. №. 1. P. 26-35. 30. Ostroumov S.A., Widdows J. Effects of cationic surfactant on mussels: inhibition of water filtration//Moscow University Biological Sciences Bulletin. 2004. Vol. 59. № 4. P. 29-33. 31. Solomonova E.A., Ostroumov S.A. Tolerance of an aquatic macrophyte Potamogeton crispus L. to sodium dodecyl sulphate//Moscow University Biological Sciences Bulletin. 2007. Vol. 62. № 4. P.176-179.
Номер: 6; Год: 2013, Страницы: 84-86; http://scipeople.ru/publication/120009/

Aim: To study the redistribution of microelements in bone tissue in osteosynthesis in high-altitude destinations. Material and Methods. The study was performed on 72 mongrel dogs of both sexes aged 1-3 years, weighing 10—15 kg. 32 dogs have been experienced the extended leg in lowlands destinations, another group of 32 animals have been experienced elongation produced in high-altitude destinations. The control group consisted of 8 healthy dogs of low mountain areas. The standard technique of surgery has been used in the research. Microelement composition has been studied by atomic absorption spectrophotometer AAS-1 N (Germany) in the long bones and the distraction regenerate. Shapiro —Wilk test was applied to analyze the normality. The data evaluation has been done by Student's t-test for unpaired samples. Results. Calcium and microelement imbalance has been obtained during transosseous osteosynthesis in high-altitude destinations, which causes functional changes in the musculoskeletal system, with similar clinical picture of Kashin — Beck. In the conditions of high-altitude destinations elongation of bones causes changes in microelements in the distraction regenerate. Conclusion. During distraction osteosynthesis in high-altitude destinations phase changes of microelements have been formed in the bone regenerate, which prognoses physiologically the formation of a false joint.
Erokhin A.N., Isakov B.D., Nakoskin A.N. Microelement content of bone tissue in transosseous osteosynthesis by II-izarov technique in high-altitude destinations (experimental research // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 1, 2014, pp. 119-123

The research goal is to examine the interrelation of cytokines level (INF-y, TNF-a, IL-2, IL-4, IL-10) and concentration of microelements in blood of patients with hemorrhagic fever accompanied by renal syndrome. 292 patients aged 18-59 years have been examined.Enzyme immunodetection has been carried out by using reagents from «Vector-Best» (Novosibirsk). The content of microelements in blood plasma has been estimated by mass spectrometry with inductively coupled plasma (ICP-MS; Elan-9000, PerkinElmer, USA) and atomic emission spectrometry with inductively coupled plasma (ICP-OES; Optima-2000 DV, PerkinElmer, USA). A direct correlation between zinc, selenium, the level of IL-2 and lead, aluminum, the level of TNF-a has been found out. The negative correlation between aluminum concentration and the level of IF-y has been determined
Khasanova G.M. Level of circulating cytokines and microelements in patients with hemorrhagic fever accompanied by renal syndrome // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 863-865