Research Objective: Evaluate the indicators of mineral metabolism in HIV-infected patients, patients with chronic hepatitis С and co-infection HIV/HCV. Material and Methods: The content of microelements (zinc (Zn), copper (Cu), iron (Fe)) in serum was determined by atomic absorption spectrophotometry. The study involved 99 patients: with chronic hepatitis С — 32 patients, with HIV infection — 34 and co-infection of HIV/HCV — 33 patients. Results: Microelements and metal-dependent proteins metabolic disorders as a reduction of the zinc, haptoglobin contents, and an increase of copper, iron, and ceruloplasmin contents were identified in patients with chronic hepatitis С In HIV-infected patients and patients with co-infection HIV/HCV were identified reducing zinc, copper, iron, haptoglobin, ceruloplasmin. in patients with co-infection HIV/HCV compared HIV-infected patients lower zinc, haptoglobin, ceruloplasmin contents (p<0,001) were detected. In patients with co-infected HIV/HCV, as compared with a group of chronic hepatitis С were set lower values of all parameters (p<0,001). Conclusion: Integrated assessment of the degree of deviation from the control of the trace element content and activity metal-dependent enzymes showed that its highest significance was typical for patients with co-infected HIV/HCV, which is higher than that of HIV-infected patients in the 1,2-fold and 2,2-fold in patients with chronic hepatitis С
Yurko Е.М. Assesment of mineral metabolism in patients with HIV-infection, chronic hepatitis с and co-infection HIV/ chronic hepatitis С // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 4, 2014, pp. 617-622

The goal: to give a characteristic of the personality profile, a comparative evaluation of psychosomatic changes in patients with psoriasis and HIV-associated psoriasis. Materials and methods. The study involved 27 patients aged 18-65 years with psoriasis and HIV-associated psoriasis, and isolated comorbid mental disorders and patients without skin disease, formed the control group. The survey in all patients was conducted with clinical-dermatological method, supplemented by psychometric methods (Hospital Anxiety and Depression Scale (HADS), the Hamilton Scale for Depression (HDRS)). Results. Analysis of the psychological status of patients with psoriasis demonstrated a high frequency of mental disorders in these patients.
Morrison А.V., Utz S.R., Davydova А.V., Grishina V.B., Platonova A.N., Shtoda U.M. The characteristics of personality profile of patients with HIV-associated psoriasis // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 552-556

The purpose of the research was detection of markers of systemic inflammatory response syndrome together with levels of markers of gram-negative endotoxinemia in HIV-patients for evaluation of role of endotoxin in immune system hyperactivation and progression of disease. Material and methods. Evaluation of levels of endotoxin, sCD14, interleu-kin 1(3, TNF-a and C-reactive protein was done in 232 HIV-positive patients. LAL-test, ELISA and biochemical tests were used. Results. The statistically significant increase of levels of all markers of systemic inflammatory response which were investigated was detected in the group of HIV-positive patients, comparing to group of healthy individuals. Direct correlation of sCD14 level with most of markers of systemic inflammatory response was found. Increased level of sCD14 was associated with more prominent clinical and laboratory signs of immunosupression. Conclusion. These results confirm a role of endotoxin which is a marker of microbial translocation and highly active biological substance in pathogenesis of immune system hyperactivation and progression of HIV-infection.
Khasanova G.K., Bikkinina О.I., Anokhin V.A. Microbial translocation and systemic inflammatory response in HIV-infection // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 508-512

The research goal is to determine the clinical pathogenetic efficacy of Cycloferon liniment in the combined therapy of periodontitis in patients with subclinical stage of HIV-infection. Medical examination and treatment of 40 patients has been carried out. It is established that use of liniment Cycloferon in the combined treatment of patients with subclinical stage of HIV-infection allows to accelerate process of normalization of lipid peroxidation parameters and antioxidant potential of blood and to decrease infection (herpes symplex virus I, Candida albicans, staphylococcus aureus) in par-odontal recess and evidence of local inflammation. The considered method of therapy has been proved to improve convalescence period and to decrease frequency of parodontitis recurrences
Oseeva А.О., Soboleva L.A., Bulkina N.V., Shuldyakov A.A. Modern approaches to parodontitis therapy in HIV patients // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 910-912

The article presents the study of formation mechanisms and periodontitis course in patients with subclinical stage of HIV-infection. The examination of 45 patients has enabled the division of patients into three basic groups: patients with periodontitis and HIV-infection; patients with periodontitis; and HIV patients without periodontitis. It has been determined that the patients with periodontitis and subclinical HIV-infection have developed local inflammatory reaction with infection, activation of anti-inflammatory cytokines in parodontal recess fluid. It has been proved that the causative factor of frequent and durable relapses in parodontal pathology with clinical HIV-infection was the development of pathologic process with endotoxicosis syndrome and imbalance of lipid peroxidation and antioxidant system
Oseeva А.О., Soboleva L.A., Bulkina N.V., Shuldyakov A. A. Periodontitis in HIV patients // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 3, 2011, pp. 681-683

Background: Prevention of accidents and management of exposures in the work environment is an important oc¬cupation health issue. This study objective was to investigate the occupational risk of HIV among Nigerian dental sur¬geons. Methods: This descriptive cross sectional survey of 300 dental surgeons practicing in private and government owned dental centers in Nigeria was conducted from June 2006 to January 2007. Results: Percutaneous injury was recorded among 69.3% of respondents and only 1.2% had Post exposure prophylaxis. Those with abraded skin that will treat patient without additional barrier were 8.6%. Percutaneous injury was positively related to gender, position, additional qualifications (p<0.05). Conclusion: Percutaneous injury is significantly high and low preventive measure at such exposure. Policies, practices, and trainings geared towards protecting and reducing the prevalence of percu¬taneous injury among dental surgeons, and improving post exposure prophylaxis uptake in the event of exposure is a necessity
C.C. Azodo Occupational risk of HIV infection among dental surgeons in Nigerian // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 2, 2010, pp. 357-360

The difficulties while conducting the differential diagnosis between systemic lupus erythromatosis (SLE) and HIV infection due to their clinical resemblance are reflected in this article
Е.Н. Скрябина, Н.А. Магдеева, И.Ф. Нам Systemic Lupus Erythromatosis or Hiv Infection «Mask»? // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 3, 2009, pp. 444-446