Objective: To examine health of children born by means of ART according to Perinatal Center of Saratov region for the last 2 years. Material and Methods: 70 pregnant women and 96 newborns with the use of ART were under examination. The causes of premature birth by women with ART, high degree of disease incidence among newborns and mortinatality are considered (рассматриваются) in the article. Results: The important factors of amnionic membranes breaking are distinguished: maternal age, multifetation, genital and extragenital pathology, antenatal infections and fetation anomaly. Highly premature babies cause not only high neonatal disease rate and disability, but also are key element in procreational loses. Women with congelated embryo transfer less often experience premature birth, also disease rate and neurologic abnormalities are less frequent. Two and more embryo transfer more often leads to habitual miscarriage. Conclusion: Mothers-to-children health indicators after using ART demonstrate the necessity of prenatal diagnostics improvement and taking measures in monitoring such women and newborns. High quality preimplantation preparation plays a major role in fetus pathology reduction. Prescriptions and counter indications to this procedure should be thoroughly evaluated; no more than 1-2 ova should be transferred.
Chernenkov Yu.V., Nechaev V.N., Stasova Yu.V. Estimation of health indicators of children born by means of application of reproductive technologies // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 4, 2014, pp. 683-688

Objective: to reveal and estimate dependence between a long waterless interval, infectious process at mother and pathology of newborn children. Material and Methods: Supervision and research have been carried out in Perinatal Center of Saratov region for the last 2 years. 167 women and 173 newborns were included in the research. The big group was composed by prematurely born children. Women were divided into 2 groups depending on infectious process of patrimonial ways and on duration of a waterless interval. Children were divided on gestation term. Results: fetoplacental insufficiency and threatened miscarriage are the main factors of extremely immature children birth. Under these conditions, prolongation of pregnancy and preparing a fetus to labor act are important factors for improving the adaptive capacity of a premature baby. One of the important factors of insolvency is membranes infection. It is a distinct disease or a result of complications of pregnancy prolongation in women with PROM, is a precursor of systemic inflammatory response and in the majority of newborns was realized in infectious process. Conclusion. Women with infectious pathology of birth canal should be thoroughly sanitized, preventive treatment should be carried out, it would prevent the implementation of fetus infection, reduce posthypoxic disorders and incidence of preterm birth and IUGR. Long PSU without infectious support contributes to a lesser extent implementation of infection in fetus and less effect on a child's neurological status.
Chernenkov Yu.V., Nechaev V.N., Lisitsyna A.S. Assessment of health state of newborns depending on duration of waterless interval and infectious process at mother // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 3, 2014, pp. 427-431