Objective: to reveal and estimate dependence between a long waterless interval, infectious process at mother and pathology of newborn children. Material and Methods: Supervision and research have been carried out in Perinatal Center of Saratov region for the last 2 years. 167 women and 173 newborns were included in the research. The big group was composed by prematurely born children. Women were divided into 2 groups depending on infectious process of patrimonial ways and on duration of a waterless interval. Children were divided on gestation term. Results: fetoplacental insufficiency and threatened miscarriage are the main factors of extremely immature children birth. Under these conditions, prolongation of pregnancy and preparing a fetus to labor act are important factors for improving the adaptive capacity of a premature baby. One of the important factors of insolvency is membranes infection. It is a distinct disease or a result of complications of pregnancy prolongation in women with PROM, is a precursor of systemic inflammatory response and in the majority of newborns was realized in infectious process. Conclusion. Women with infectious pathology of birth canal should be thoroughly sanitized, preventive treatment should be carried out, it would prevent the implementation of fetus infection, reduce posthypoxic disorders and incidence of preterm birth and IUGR. Long PSU without infectious support contributes to a lesser extent implementation of infection in fetus and less effect on a child's neurological status.
Chernenkov Yu.V., Nechaev V.N., Lisitsyna A.S. Assessment of health state of newborns depending on duration of waterless interval and infectious process at mother // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 3, 2014, pp. 427-431

В статье анализируются причины роста аномалий развития плода и новорожденного от женщин группы риска по этой патологии. Предлагается программа ранней пренатальной и постнатальной диагностики, профилактики и коррекции врожденных пороков развития. Реализация предложенного комплекса мероприятий позволила повысить возможности выявления врожденных пороков развития, снизить число инкурабильных случаев, уменьшить летальность и инвалидность
Yu.V.Chernenkov, V.N. Nechaev DIAGNOSTICS, PROPHYLAXIS AND CORRECTION OF CONGENITAL MALFORMATION DEVELOPMENT // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 3, 2009, pp. 379-383