Aim: organization and follow-up of a registry of patients with cerebrovascular disease in in special department. Materials and methods. In the period from January 2011 to December 2013 all cases of cerebrovascular disease in the special department were recorded. Each patient had an electronic case book and thematic record, developed on the basis of the materials of the National Stoke Association of "Registry of stroke." Results. 418 cases of cerebral stroke were registered. Male to female ratio was 3.7: 1. Patients with initial diagnosed cerebral stroke were 78%, secondary 22%. The average age of patients was 63. The big number of strokes was observed in men aged 56-57 years; in women aged 75-77 years. TOAST criteria for subtypes of ischemic stroke were distributed to: atherothrombotic (29,3%), cardioembolic (29,1 %), 22,4% lacunar ischemic stroke due to other established reasons (8,8%), crptogenic (10,4%). Hemorrhagic stroke was observed in 16.8% of cases. Parenchymal hemorrhage was observed in 10.7% of cases, nontraumatic subarachnoid hemorrhage (4,5%). Among the risk factors in patients with ischemic stroke identified: arterial hypertension (88,9%), coronary heart disease (43%), heart rhythm disorders (28,4%), diabetes (18,6%). The proportion of endovascular interventions performed for 3 years was 31.2%. Mortality rate was 3.74% (10 people) in 2011; 4.65% (14 people) in 2012; 2.48% (7 people) in 2013. Conclusion. Follow up the hospital stroke registry allowed to estimate the structure andcourse of cerebral stroke, found the risk factors to identify the most important factors of death.