Magnetic Nanoparticles Promise to Prevent Strokes and Heart Attacks./Лавренова.Ю.О., Столярова Е.А.//Научный руководитель: Храмова Юлия Анатольевна/ГБОУ ВПО Саратовский ГМУ им. В.И. Разумовского Минздрава России  Кафедра иностранных языковMagnetic nanoparticles have served as the foundation for a number of medical technologies, including drug delivery, medical imaging contrast agents and cancer diagnosis and treatment.Now researchers at Houston Methodist are loading up magnetic nanoparticles with drugs and camouflaging them from the immune systems so that they can destroy blood clots at a rate about 100 to 1000 times faster than a commonly used clot-busting technique.The albumin, which creates the outer cover, provides a sort of camouflage, giving the loaded nanoparticles time to reach their blood clot target before the body's immune system recognizes the nanoparticles as invaders and attacks them.  Iron oxide was chosen for the core because the researchers plan to use them for magnetic resonance imaging, remote guidance with external magnetic fields, and for further accelerating clot dissolution with localized magnetic heating. The clot-busting drug loaded into the nanoparticles is tPA, (tissue plasminogen activator), an enzyme that is also found naturally in blood at low concentrations.  Typically, a small volume of concentrated tPA is injected into a stroke patient's blood upstream of a confirmed or suspected clot.  From there, some of the tPA reaches the clot, but much of it may cruise past or around the clot, potentially ending up anywhere in the circulatory system.  tPA is typically used in emergency scenarios by health care staff, but it can be dangerous to patients who are prone to hemorrhage.Overall, these nanoparticles may represent an advance in preventing heart attacks, strokes and pulmonary embolisms.  Further safety and effectiveness studies are still required to achieve human clinical trials.  “We are optimistic because the FDA has already approved the use of iron oxide as a contrast agent in MRIs,” Paolo Decuzzi the study's co-principal investigator said.  “And we do not anticipate needing to use as much of the iron oxide at concentrations higher than what's already been approved.  The other chemical aspects of the nanoparticles are natural substances you already find in the bloodstream.” Decuzzi said that his group will continue to examine the feasibility of using magnetic fields to guide and heat the nanoparticles.
Лавренова Ю.О., Столярова Е.А. Magnetic Nanoparticles Promise to Prevent Strokes and Heart Attacks. // Бюллетень медицинских Интернет-конференций, Vol. 5, Issue 12, 2016, pp. 1603-1603

Spontaneous and traumatic dissection of vertebral arteries can cause ischemic or hemorrhagic strokes in young individuals. Clinical features often propitiate a challenging diagnosis because initial presentations are variable, from asymptomatic till very ominous conditions. Therefore, an elevated index of suspicion and use of imaging resources might favor early diagnosis and prevention of serious consequences. We report a healthy 21-year-old man who had a motorcycle accident about fourty days before the imaging confirmation of vertebral artery dissection and thrombosis of the basilar artery. The patient successfully underwent non invasive management, with use of acetylsalicylic acid.
Vitorino Modesto dos Santos, Ursula Valeska Poti Araújo Lima, Renata Faria Silva, Silvana Alves Gomma de Azevedo, Melissa Gebrim Ribeiro, Daniela Gomes Gebrim A 21-year-old man with late Wallenberg syndrome after a motorcycle trauma // Russian Open Medical Journal, Vol. 4, Issue 3, 2015, pp. 0-0

Aim. The study of virtual reality technology in the rehabilitation of patients with cerebral stroke and influence on post stroke affective disorder. Materials and methods. The study included 88 patients with ischemic stroke: 59 men (67%) and 29 women (33%). The average age of the patients was 62,05 ± 11,74 years. In the study group included 46 patients, 44 patients in the control group. The groups were matched by age, time from the begin of disease, severity of disease, the severity of motor, affective and cognitive impairments. In addition, in the study group to the program of early rehabilitation to use individual training with virtual reality technology (BTS NIRVANA). The duration of the training was 21 days, 3 times a week for 40 minutes. Results. On the background of rehabilitation in the study group patients had a significant reduced of neurological deficit (p <0,05). Significantly improved neurodynamic and executive cognitive function (p <0,01). In the study group was a statistically significant decrease symptoms of depression on a scale of BDI was 31,7% vs. 20.9% in the control group, anxiety on a scale of HADS was 18,46% (p <0,05) vs. 12,23% (p <0,05) in the control group. Increase motivation and decrease symptoms of apathy in the study group of patients on a scale of AES-C was 13,78% (p <0,05) vs. 1,01 % in the control group. On the background of rehabilitation patients in the study group was no difference between the rates of pathological muscle and mental fatigue. On the background there is rehabilitation of the quality of life due to mobility and activities of daily living. Conclusion. The study showed the positive effect of virtual reality technology for the correction of post-stroke mood disorders.
Maslyuk О.А., Smolentseva I.G., Amosova N.A., Shevchenko N.S., Milagina V.S. Using of virtual reality technology in acute cerebral stroke and their influense on post-stroke affective disorders // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 4, 2014, pp. 824-827