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 Найдено научных статей и публикаций: 2, для научной тематики: KRAS


Связанные научные тематики:
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1.

Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity, In Silico and In Vitro Study of Their Molecular Targets as PDE4B. (публикация автора на scipeople)     

Lapa GB, Tsunoda T, Shirasawa S, et al - Chem Biol Drug Des. , 2016
To examine the cytotoxic activity of congeners of 3-amino-isoquinoline, we performed the phenotypic screening using panel of 60 cell lines and found that...
2.

Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing (публикация автора на scipeople)     

Moskalev E.A., Stöhr R., Rieker R., Hebele S., Fuchs F., Sirbu H., Mastitsky S.E., Boltze C., König H., Agaimy A., Hartmann A., Haller F. - Virchows Archiv , 2013
Detection of activating EGFR mutations in NSCLC is the prerequisite for individualised therapy with receptor tyrosine kinase inhibitors (TKI). In contrast, mutant downstream effector KRAS is associated with TKI resistance. Accordingly, EGFR...