Aims. The present research aimed the study of the fuorescence of endogenous porphyrins of the skin in patients with acne. Material and methods. 20 patients with acne of 1 – 2 degrees of severity were selected. The main research methodology was a selective colorimetry of tissues with using an electronic photographic devices. The research was led with the use of multiple flters. Image areas were synthesized with high fuorescence, and then a combination of these areas with the source image was produced. The images were processed in ImageJ. Results. The examined patients has revealed intensive red glow in the feld of acne-elements before treatment. After the work with an orange flter pictures were more informative. The study suggests that the chosen method for identifcation of quantitative composition of P. acne appears to be noninvasive and highly effcient.