The aim of the article is to present the clinical experience of conducting the patient with a congenital disease (mandibulo-facial dysostosis) resulting from defeat of the structures proceeding from the first branchial arch. The pathological state is inherited on autosomno-dominanttype. The disease can be observed in two or even three generations. The supervision represents a great interest from the clinical point of view as it rarely occurs in daily practice. Early diagnostics of difficult genetic syndromes and the clinical supervision described represent significant difficulties. According to the research, in similar situations statement of the syndromal diagnosis with specification of anomalies of development on the basis of the analysis of clinical data, additional methods of inspection, with the subsequent surgical correction of the broken functions has been justified.

The goal of the research is the comparative analysis of a quality of life and quantitative characteristics of a chronic tense headache as well as the studying of adaptive reactions. 123 women (middle age 42,6±2,3) with initiatory stages of chronic tense headaches have been examined using diagnostic criteria of the International classifcation of headache disorders (ICDH — II, 2003), headache diary and the McGill Pain Questionnaire. Headache intensity was estimated by the Visual Analog Scale. Monitoring quality of life (QOL) was organized in a form of a questionnaire SF-36. An adaptive reactions type was analizing by L. Kh. Garkavi. Clinical implications and quantitative characteristics of a chronic tense headache, condition of vegetative and emotional sphere, and also quality of life and adaptive reactions are studied. Infuence of chronic headache on various components quality of life was investigated. Monitoring of physical, psychological and social functioning of patients with reception of differential and integrated quantity indicators of QOL, and also the analysis of adaptic reactions will give the chance to the doctor to develop a complex of practical references on treatment chronic tense headache at patients with poor quality of life and adverse adaptive reactions.