Aim: to study the effect features of combined use of pelotherapy and phytocomplex on main clinical symptoms regress and quality of life in patients with knee joint osteoarthrosis. Material and Methods. The study included 96 patients with knee joint osteoarthrosis; the effectiveness evaluation was estimated in terms of American Rheumatologic Association (ARA), the data of visual-analogue scale (VAS), goniometry and laser Doppler flowmetry, indexes WOMAC, Lekena and the index of activity SIA, criteria of life quality questionnaire HAQ. Results. The complex use of pelotherapy and phytocomplex in conjunction with a drug treatment of patients have a more pronounced positive effect on pain (by 35-36%), function of the knee joint (by 26-28%), microcirculation (1.5-2 times) and the quality of life (by 22-25%) compared to treatment with only drug treatment or combined using of ultrasound and drug therapy. Conclusion. The new method of combined use of pelotherapy and phytocomplex leads to the evident regress of clinical symptomatology at patients with knee joint osteoarthrosis, improves locomotor function, microcirculation of knee joints and quality of life.
Kotenko К.V., Babaskin D.V. The combined use of pelotherapy and phytocomplex in rehabilitation of patients with knee joint osteoarthrosis // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 4, 2013, pp. 946-950

Objective: the comparative research of phytocomplex phonophoresis rehabilitation efficiency of patients with knee joint osteoarthrosis. Material and Methods, the study included 100 patients with knee joint osteoarthrosis; the effectiveness evaluation was made in terms of American Rheumatologic Association (ARA), the data of visual-analogue scale (VAS) and goniometry, indexes WOMAC, Lekena and the index of activity SIA, criteria of life quality questionnaire HAQ. Results. The complex use of phyto- and ultrasonic therapy in conjunction with an medicamentous treatment of patients have a more pronounced positive effect on pain (by 26-28%), function of the knee joint (by 22-26%) and the quality of life (by 24%) compared to treatment with medicamentous only treatment or combined using ultrasonic and medicamentous therapy. Conclusion. The new method of phytocomplex phonophoresis leads to the expressed regress of clinical symptomatology at patients with knee joint osteoarthrosis, improves locomotor function of knee joints and quality of life.
Kotenko К.V., Babaskin D.V. Efficiency assessment of phytocomplex phonophoresis in rehabilitation of patients with knee joint osteoarthrosis // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 4, 2013, pp. 942-946

The method of global electromyography has been used for the evaluation of 231 patients aged from 16 to 74 (43,7±0,8) with bilateral osteoarthrosis of major joints of lower extremities I-III degrees before the course of conservative treatment, immediately after the end of conservative treatment and in three months. Conservative treatment of patients with osteoarthrosis of major joints of lower extremities has been shown to cause restructuring of EMG patterns of maximal voluntary muscle contraction in lower extremities accompanied by decreased asymmetry of activity levels in muscle pairs and less observations of pathologically changed EMG that results in improved functional condition of the locomotor system.
N.V. Sazonova, М.S. Sayfutdinov Functional Muscular Condition Dynamics at Osteoarthrosis Conservative Treatment of Major Joints of Lower Extremities // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 2, 2009, pp. 250-254

During the assessment of peculiarities of bone tissue remodelling in inflammatory and non inflammatory lesions of hip joint, according to the levels of biochemical indices in the blood serum, some unilateral changes of bone tissue metabolism have been revealed in advanced rheumatoid arthritis and osteoarthrosis. More severe disturbances of bone remodelling in case of rheumatoid arthritis are obviously connected with peculiarities of the rheumatoid inflammation pathogenesis.
E.V. Karyakina, E.A. Persova Some Peculiarities of Bone Tissue Remodelling at Hip Joint Inflammatory and Degenerative Diseases // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 2, 2009, pp. 227-230

The date on risk factors, some aspects ofpathogenesis and modern principles ofosteoarthrosis therapy are covered in the review.
V.A. Mitrofanov, I.I. Zhadyonov, D.M. Puchinyan OSTEOARTHROSIS: RISK FACTORS, PATHOGENESIS AND MODERN THERAPY // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 2, 2008, pp. 23-30