Purpose: to define regularities of variability of bone structures of a hip joint depending on type of dysplastic coxarthrosis and to develop tactics of total endoprosthesis replacement. Objects of research. 106 patients with dysplastic coxarthrosis of varying severity, passing treatment on the basis of Federal State Budget Institution of Saratov Scientific Research Institute of Traumatology and Orthopedics from 2005 to 2014 applying methods X, KT-, MRT-metry variation and statistical methods. Results: According to anatomic features of a hip joint at dysplastic coxarthrosis of various types algorithms of choice of acetabularand femoral components of endoprosthesis, and also tactics of total endoprosthesis replacement in groups of research are developed. Conclusion. The choice of a standard size of an endoprosthesis of a hip joint needs to be carried out taking into account X-ray anatomic features of a hip joint and degree of expressiveness of the dysplastic changes. At dysplastic coxarthrosis of the l-ll types it is necessary to carry out standard total endoprosthesis replacement; at coxarthrosis of the III type —total endoprosthesis replacement in combination with plasticity of a roof of acetabular hollow; at coxarthrosis of the IV type — total endoprosthesis replacement in a combination from the shortening femur osteotomy.
Norkin I.A., Anisimova Е.А., Voskresensky O.Yu., Yusupov K.S., Anisimov D.l., Letov A.S., Popryga D.V., Popov A.N. Morphometric justification of algorithm of the choice of method of surgical treatment of dysplastic coxarthrosis // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 2, 2015, pp. 182-186

Research objective is to estimate stressful remodelling features of bone tissue according to the densitometry data and to the level of biochemical markers of bone resorption and formation in total hip replacement (THR). Bone tissue mineral density (BTMD), condition of calcium-phosphoric metabolism and biochemical markers of bone formation (osteocalcin and bone isoenzyme of alkaline phosphatase) and resorption (С-terminal bodypeptide of the I type collagen) have been determined in 52 patients with coxarthrosis of ll-lll stages with marked joint dysfunction before and after THR. The control group included 24 donors. The data were considered to be reliable when the probability index was р<0,05. The reliable (р<0,05) change of BTMD was determined only in 3-6 months after the operation, whereas the change of biochemical markers of remodeling had already been done after 1,5-3 months, allowing to define the group of patients with obvious negative bone balance: strong predominance of resorption processes without compensation of the subsequent adequate osteogenesis, that subsequently could lead to significant bone tissue deficiency in the area adjacent to the endoprosthesis. Changes of indices of calcium-phosphoric metabolism were not certain during the investigation term. ln conclusion it is to state that biochemical markers of remodeling in comparison with BTMD allow to estimate objectively features of adaptive bone tissue remodeling after THR in earlier periods and to define group of patients with sharp intensification of metabolism and obvious negative bone balance
E.V. Karjakina, E.A. Persova, E.V. Gladkova Instrumental and laboratory assessment of stressful remodelling processes in bone tissue at total hip replacement // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 2, 2010, pp. 423-428

During the assessment of peculiarities of bone tissue remodelling in inflammatory and non inflammatory lesions of hip joint, according to the levels of biochemical indices in the blood serum, some unilateral changes of bone tissue metabolism have been revealed in advanced rheumatoid arthritis and osteoarthrosis. More severe disturbances of bone remodelling in case of rheumatoid arthritis are obviously connected with peculiarities of the rheumatoid inflammation pathogenesis.
E.V. Karyakina, E.A. Persova Some Peculiarities of Bone Tissue Remodelling at Hip Joint Inflammatory and Degenerative Diseases // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 2, 2009, pp. 227-230