Связанные научные тематики:
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 Найдено научных статей и публикаций: 3, для научной тематики: Multitargeted drugs

1.

Computer-assisted prediction and design of multitargeted drugs (публикация автора на scipeople)   

Poroikov V.V. - Med. Chem. Res. , 2010
During the XX century the dominant paradigm in creation of new drugs was based on suggestion about selectivity of action on a certain molecular target, which should lead to the normalization of pathological process. At the same time, the majority of known drugs interact with several or even many tar...
2.

Computer-aided prediction of potential antineoplastic agents. (публикация автора на scipeople)   

Zakharov A., Lagunin A., Filimonov D., Poroikov V. - Chemistry Central Journal , 2008
Rational selection of potential antineoplastic agents with multitargeted action is considered on the basis of computer prediction of biological activity spectra using PASS program....
3.

Computer-aided selection of potential antihypertensive compounds with dual mechanisms of action (публикация автора на scipeople)   

Lagunin A.A., Gomazkov O.A., Filimonov D.A., Gureeva T.A., Dilakyan E.A., Kugaevskaya E.V., Elisseeva Yu.E., Solovyeva N.I., Poroikov V.V. - Journal of Medicinal Chemistry , 2003
The prediction of biological activity spectra for substances as an approach for searching compounds with complex mechanisms of action was studied. New compounds with dual mechanisms of antihypertensive action were found by this approach. Biological activity spectra for substances were predicted on t...