At 49 patients, engaged intensive brainwork, clinically and by heart rate variability method investigates a condition of vegetative nervous system. Initially at the majority of patients normal parameters were recorded. To 30 patients of the basic group has been followed a course of color therapy with the purpose to study infuence of a color therapy of a vegetative regulation at the given patients. Green, yellow, orange and red colors were used. 19 persons have made a check-group. They were the patients who did not have a course of color therapy, the parameters of a condition of vegetative nervous system improved or were the same. In group of the control there was an attrition of a vegetative regulation. There is a long intensive intellectual activity exhausts a vegetative regulation related in the research. The 10-days course of color therapy authentically promotes maintenance of a condition of vegetative nervous system at a level of due functioning.