The purpose of the study, to improve the quality of treatment of mild periodontitis based on clinical and microbiological studies on the effectiveness of pharmacotherapy by liniment of cycloferon. Research methods. Clinical study included 50 patients aged 20-50 years old with mild periodontitis in the acute stage. Liniment of cycloferon was applied on the gums two times a day in 10-12 hours for 14 days. Microbial picture of oral mucosal and periodontal pockets in patients with periodontitis were analyzed twice before the treatment and at 30-31-day of observation according to the detection of microorganisms by polymerase chain reaction (PCR). Results. The dynamics on the background of pharmacotherapy in patients with mild periodontitis with liniment of cycloferon showed a significant decrease in the frequency of identification of pathogenic flora, compared with conventional therapy of periodontitis, the disappearance of complaints and the main clinical manifestations of periodontitis. Conclusion. The accelerated recovery of patients with periodontitis decreasing frequency of relapses by pharmacotherapy using liniment of cycloferon accompanied by sanogenic effects for microbial associations of periodontal pockets and oral mucosa showed pathogenic focus and efficiency of the drug in periodontitis.
Zaitseva Е.М., Eremin О.V., Ivaschenko Y.У., Mekhtieva R.R., Nelovko Т.V. Efficacy of pharmacotherapy in patients with mild periodontitis by liniment of cycloferon // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 3, 2013, pp. 390-393

In this paper we present a study of the contents of periodontal pocket in patients with a diagnosis of chronic generalized periodontitis mild, moderate and severe. Defined genera and species affiliation of anaerobic bacteria by various methods of diagnosis. We found a decreasing trend in the number of associations of microorganisms in periodontal pockets, as the weighting of the pathological process
Morgunova V.M. Microbiological characteristics of the contents of periodontal pockets of patients with periodontitis adolescents // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 312-314

By data the CART, about 95 % of adult population of a planet signs of periodontal diseases have
Bavykina T.Ju., Salivonchik M.S., Ryzhova I.P., Chuev V.V. Perfection of definitive processing of tooth artificial limbs from thermoplastic polymers // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 271-272