Найдено научных статей и публикаций: 1, для научной тематики: In silico prediction
1.
Prasad Y.R., Raja Sekhar K.K., Shankarananth V., Sireesha G., Swetha Harika K., Poroikov V.
- Journal of Pharmacy Research , 2011
The objective of the present work was to synthesize and estimate mechanism of action, pharmacological activity and toxic or side effects of some 1,3,5-trisubstituted-2-pyrazoline derivatives. Substituted chalcones were used as starting material. Chalcones comprising aryl moiety have been prepared by...
The objective of the present work was to synthesize and estimate mechanism of action, pharmacological activity and toxic or side effects of some 1,3,5-trisubstituted-2-pyrazoline derivatives. Substituted chalcones were used as starting material. Chalcones comprising aryl moiety have been prepared by Claisen-Schmidt condensation of aromatic aldehydes with 4-Hydroxy acetophenone. All these pyrazoline derivativatives are characterised by IR, 1H-NMR and MS analysis. Prediction of Activity Spectra for Substances(PASS) is the computer program used in this work.Antifungal and antibacterial activities predicted by PASS was confirmed by experimental evaluation.
Journal of Pharmacy Research, 2011, 4 (2), 558-560.
