This article presents the results of 116 radical cystectomies of patients with bladder cancer. In all the cases various generated modifications of orthotopic bladder including the authors' methodology have been carried out. The structure of complications during the post-operative period has been analyzed. Various complications occurred in 16,4 % of patients. In 3,4 % of cases they caused death. In 74% of cases direct dependence of postoperative complications on advanced tumorous process and severity of accomponied pathology has been identified. Direct dependence on the selection of method of urine derivation has not been found. Five-year cancer survival rate accounted 70 %. The study of patients' quality of life has been performed using EORTC-QLQ-C-30. High indices have been worked out. Dependence on the method of orthotopic bladder creation has been negligible
V.A. Atduev, A.B. Stroganov, Yu.O. Lyubarskaya, D.S. Ledyaev, V.V. Schutov, G.A. Berezkina, H.M. Mamedov, A.A. Bazaev Results Of Orthotopic Bladder Creation After Radical Cystectomy In Patients With Bladder Cancer // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 4, 2009, pp. 615-619

On the basis of surgical and biopsy material 106 patients with diseases of urinary bladder have been under study. They received treatment at Scientific Research Institute of Fundamental and Clinical Uronephrology of Saratov State Medical University. 13 immunohistochemical markers have been evaluated: markers of proliferative activity - Ki-67, PCNA, p63, suppressor of tumor growth - p53, markers of apoptosis - Bcl-2, Bax, receptor of epidermal growth factors - EGFR, cytokeratin profile - (CK7, CK8, CK10/13, CK 17, CK18, CK19), as well as their diagnostic significance for identifying the urinary bladder cancer
G.N. Maslyakova, A.N. Ponukalin, E.N. Tsmokalyuk, A.B. Bucharskaya, A.V. Medvedeva Significance Of Immunohistochemical Markers In Diagnostics Of Urinary Bladder Cancer // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 4, 2009, pp. 608-611