The relevance of the problem is conditioned by the need to change the extensive way of education development. It is impossible to increase the base of specific knowledge indefinitely. Today, something else is required: modern and intellectual education. The article is aimed at finding the way for an efficient combination of professional and fundamental education by establishing interdisciplinary relations of mathematics and physics with specialization disciplines. The current stage in the development of science is characterized by the interpenetration of sciences into each other, and especially by the penetration of mathematics and physics into other branches of knowledge. As a result, we proceed from the definition of physics as a science that studies the structure and properties of matter — substances and fields — and the forms of matter existence — space and time. This definition does not imply the reduction of all natural science to physics, but it means that the final theoretical bases of any field of natural science are of a physical nature. The materials of the article can be useful for professors of mathematics and physics in technical universities who need to know the content of specialization disciplines in order to understand what mathematical knowledge is particularly necessary for the specialists in certain branches of higher technical education