Найдено научных статей и публикаций: 1, для научной тематики: Antidepressants 5-HTTLPR
1.
Иванец Николай Николаевич (профессор); Кинкулькина Марина Аркадьевна (профессор); Несвижский Юрий Владимирович (профессор)
, 2018
To identify the association between the 5-HTTLPR polymorphism of the serotonin transporter gene with the efficacy and tolerability of antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI). Materials and methods. A complex clinical-psychopathological and genetic study of 38 pati...
To identify the association between the 5-HTTLPR polymorphism of the serotonin transporter gene with the efficacy and tolerability of antidepressant therapy with a selective serotonin reuptake inhibitor (SSRI). Materials and methods. A complex clinical-psychopathological and genetic study of 38 patients with depression during SSRI treatment was conducted. Results and conclusions. Statistical associations between the 5-HTTLPR polymorphism and the levels of remission and tolerability were identified: carriers of the SS genotype rarely achieved remission and developed more severe side effects.
