Aim: working out the methods of visualization of information obtained during optical coherent tomography in normal skin and in series of inflammatory disorders. Materials and Methods. OCS1300SS (made in Thorlabs, USA) was used in which the source of emission of radiation was a super-luminiscent diode with mean wavelength of 1325 nm. 12 patients with different skin conditions and 5 virtually healthy volunteers were examined with ОСТ procedure in OPD and IPD settings. High resolution USG numerical system DUB (TPM GmbH, Germany) was used for comparative USG assessment. Results. ОСТ demonstrated considerably more detailed picture of the objects scanned compared to USG investigation. Image obtained with the help of ОСТ contains vital information about sizes of macro-morphological elements, status of vascular elements and their density in different depths of the skin. Conclusion. Additional results obtained from ОСТ of the skin lesions in plane section improves attraction for ОСТ in practical dermatology.
Utz S.R., Zimnyakov D.A., Galkina E.M., Yuvchenko S.A., Alonova I.V., Artemina E.M., Ushakova O.V. Benefits of optical coherence tomography for imaging of skin diseases // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 3, 2015, pp. 392-396

Goal: to examine the effectiveness of use low coherent reflectometry method for diagnostic purposes in clinical dermatology. Materials and methods. For measurements optical coherence tomography OCS1300SS (Thorlab, USA) with swiped frequency was used. 12 patients with different skin diseases were studied (psoriasis, acne, scleroderma, etc.). Results. Distinct border was detected between layers with different optical characteristics (and structure) at a depth of 1000 m to 2000 microns for majority of the samples studied. It is important to note that a good regerneration of distribution of the interference signal during transmission from one section to another and close to an exponential decay of signal with an increase in depth of probing. Conclusion. As a criterion of pathological changes,may be proposed the degree of spatial uniformity in distribution decay constant of interference signal in depth obtained with help of low coherent reflectometry (in vivo).
Zimnyakov D.A., Utz S.R., Galkina E.M., Yuvchenko S.A., Alonova I.V., Artemina E.M., Ushakova O.V. Low coherence re-flectometry of skin: benefits for skin imaging // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 3, 2015, pp. 376-380