The aim: to prove the necessity of professional oral hygiene before the fixation of permanent orthodontic equipment in individuals with dental and facial anomalies based on the study of biomarkers of gingival fluid. Materials and Methods: Clinical, cytological examination and gingival fluid test on cytokine levels in 80 patients. Results: In patients with dentofacial anomalies observed decline in hygiene index, and increase the content of gingival fluid neutrophils and degenerative epithelial cells. It is accompanied by an increase in the concentration of the main group of pro-inflammatory and osteogenic cytokines, growth factors. Conclusion: Preliminary conducting professional oral hygiene to orthodontic treatment in patients with dentofacial anomalies leads to the conservation values of satisfactory hygienic indices of the mouth. In this case, the increase in the content of gingival fluid neutrophils and degenerative epithelial cells, with increased concentrations of the main group of pro-inflammatory and osteogenic cytokines has been defined insignificant.
Zakharova N.B., Lepilin A.V., Vorobjev D.V., Erokina N.L., Bakhteeva G.R. The use of professional oral hygiene in orthodontic treatment on the results of studies of gingival fluid biomarkers // Saratov Journal of Medical Scientific Research, Vol. 11, Issue 2, 2015, pp. 168-173