Aim: development and scientific substantiation of a complex application halo-inhaled and flutter-kinesiotherapy in patients with chronic obstructive toxic chemical bronchitis. Material and methods. There was an examination and treatment of 125 patients with chronic obstructive toxic chemical bronchitis at the age from 32 to 65 years (average age 52.2+3,1) with industrial experience from 5 to 27 years (average age 15.9+3,9). Results. Comparative analysis revealed an advantage of an integrated application halo-inhaled and flutter-kinesiotherapy in patients with chronic obstructive toxic chemical bronchitis as in the I, and that is especially important at the II stage of the disease, which is confirmed by the regression of the main clinical symptoms, a significant decrease in the intensity index of inflammation, recovery to normal values of factors of local immunity broncho-pulmonary system. Conclusion. Developed a comprehensive program including halo-inhaled and flutter-kinesiotherapy in patients with chronic obstructive toxic chemical bronchitis has a pronounced anti-inflammatory, antibacterial and immunocorrection effect, improves bronchodilating function and bronchial obstruction in bronchial tubes of large, medium and small caliber. The absence of exacerbations in the past year proves that this method is highly effective secondary prevention of lung disease.