Связанные научные тематики:
3
Найдено научных статей и публикаций: 1, для научной тематики: 5-Dimethyl-1H-pyrazole 3-Bromoprop-1-ene Phase transfer catalysis Chemical kinetics Rational mechanism Ultrasonic irradiation
1.
Manuri Brahmayya, Maw-Ling Wang *
- Journal of taiwan institute of chemical engineers , 2014
The synthesis of 3,5-dimethyl-1-prop-2-enylpyrazole was successfully carried out by reacting the 3,5-
di-methyl pyrazole with 3-bromoprop-1-ene in small amount of KOH and organic solvent solid–liquid
phase medium under phase transfer catalysis (PTC) and almost anhydrous conditions assisted by the
ul...
The synthesis of 3,5-dimethyl-1-prop-2-enylpyrazole was successfully carried out by reacting the 3,5-
di-methyl pyrazole with 3-bromoprop-1-ene in small amount of KOH and organic solvent solid–liquid
phase medium under phase transfer catalysis (PTC) and almost anhydrous conditions assisted by the
ultrasonic irradiation in the 5 h at 50 8C. The main target of this carried work was to provide evidence
that the reaction conditions by investigation of the kinetic behaviour, activation energy, reaction
mechanism and the related parameters in the solid–liquid PTC reaction besides on to reduce time and
temperature of reaction. A rational mechanism for the reaction has been derived base on the
experimental result. This kinetic reaction follows pseudo first order rate law. A rate expression had
developed to explain the kinetic behaviours from which the apparent rate constant (kapp) of the organic-
phase reaction was obtained via investigated data. Kinetics of the reaction, including the effects of
agitation speed, quantity of potassium hydroxide, quantity of water, temperature, quantity of
tetraoctylammonium bromide (TOAB), volume of cyclohexanone, quarternary ammonium salts and
organic solvents on the conversion of RBr and the apparent rate constant (kapp) were investigated in full
length. Rational explanations for the resulting phenomena are also provided.