Найдено научных статей и публикаций: 1, для научной тематики: Sarafloxacin
1.
Parshikov I.A., Freeman J.P., Lay J.O. Jr., Moody J.D., Williams A.J., Beger R.D., Sutherland J.B.
- Journal of Industrial Microbiology and Biotechnology , 2001
To investigate the microbial biotransformation of veterinary fluoroquinolones, Mucor ramannianus was grown in sucrose/peptone broth with sarafloxacin for 18 days. Cultures were extracted with ethyl acetate and extracts were analyzed by liquid chromatography. The two metabolites (26% and 15% of the A...
To investigate the microbial biotransformation of veterinary fluoroquinolones, Mucor ramannianus was grown in sucrose/peptone broth with sarafloxacin for 18 days. Cultures were extracted with ethyl acetate and extracts were analyzed by liquid chromatography. The two metabolites (26% and 15% of the A 280, respectively) were identified by mass and 1H nuclear magnetic resonance spectra as N-acetylsarafloxacin and desethylene-N-acetylsarafloxacin. The biological formation of desethylene-N-acetylsarafloxacin has not been previously observed.
J. Ind. Microbiol. Biotechnol. 2001. V. 26. P.140-144.
