The study aims the influence of THz radiation on 129.0 GHz of atmospheric oxygen on blood pressure (BP) and pulse, hemodynamic parameters of orbital arteries during the irradiation of biological active points of application in healthy volunteers and in patients with involutional macular degeneration (IMD). It had been noticed a decrease of systolic and diastolic components of arterial pressure and pulse; a normalization of systolic velocity of bloodstream (SVB) and of resistance index (RI) in orbital arteries in patients with IMD. The result of the research is: 1) the method of THz influence of on molecular spectrum of emission and absorption of 129.0 GHz atmospheric oxygen is safe and does not cause any negative side effects on common state in healthy volunteers and in patients with IMD; 2) single of THz influence of molecular spectrum of emission and absorption of 129.0 GHz atmospheric oxygen caused a statistical important improvement in vascular system of eyeball.
Vyacheslav F. Kirichuk, Larisa E. Fedorischeva, Ksenya U. Eremenko, Anatolya F. Cypyaschuk The reaction of cardiovascular system and orbital vessels after THz irradiation of molecular spectrum of emission and absorption of 129.0 GHz atmospheric oxygen in healthy volunteers and in patients with involutional macular degeneration // Russian Open Medical Journal, Vol. 2, Issue 4, 2013, pp. 407-0

There is new information about the mechanism of THz radiation of molecular emission and absorption spectrum (MEAS) of 150.176-150.664 GHz nitrogen oxide occurrence exposure. Organized experiments let us establish the fact that a normalizing effect of THz radiation on microvasculature perfusion and functional endothelium condition in male rats under the acute stress condition is not realized after using of nitrogen oxide synthase (NOS) L-NAME. This shows that endogenic nitrogen oxide and endothelial NOS takes part in mechanisms of potentiation of positive correcting effect of MEAS of 150.176–150.664 GHz nitrogen oxide occurrence on defected parameters of skin microvasculature perfusion, and functional endothelium condition in male rats under the acute immobilization stress condition.
Vyacheslav F. Kirichuk, Evgeny V. Andronov The nitrogen oxide synthase effect in endothelium reaction and change in peripheral perfusion under THz radiation of nitrogen oxide occurrence exposure // Russian Open Medical Journal, Vol. 2, Issue 4, 2013, pp. 406-0

In this review, there is generalized material of many experimental researches in interaction of THz-waves molecular emission and absorption spectrum (MEAS) of nitrogen oxide occurrence with bioobjects. Thrombocytes and experimental animals were used as bioobjects. The experiments let indicate changes caused by THz-waves: at the cellular, tissular, system, organismic levels. There are all data of changes in physiological mechanisms of reglations at all levels: autocrine, paracrine, endocrine and nervous. There is a complex overview of experimental material firstly performed in the article. There had been shown that the effect of THz-waves of the given occurrence is realized by the changed activity of nitroxidergic system. It had been proved that THz-waves of nitrogen oxide occurrence can stimulate nitrogen oxide producing in organs and tissues in condition of its low concentration. Possible mechanisms of antiaggregative effect of the given waves had been described. There had been shown the possibility of regulating of vascular tone and system hemodynamics with the help of the studying these frequencies. The represented data of lipid peroxidation and enzymatic and nonenzymatic components of organism system under the influence of THz-waves of nitrogen oxide occurrence in stress conditions. Besides, there were shown changes of stress-regulating system activity and in concentration of important mediators - catecholamines and glucocorticosteroids. These data let characterize mechanism of realization of THz-waves basic effects. The research had shown the possibility of THz-waves of nitrogen oxide occurrence usage as a method of natural physiological noninvasive regulation of significant organism functions.
Vyacheslav F. Kirichuk, Alexander A. Tsymbal, Evgeny V. Andronov Mechanisms of realization of THz-waves of nitrogen oxide occurrence physiological effects // Russian Open Medical Journal, Vol. 2, Issue 4, 2013, pp. 404-0