Vector borne diseases are the major tropical health challenges and leading cause of morbidity and mortality in the world. Present study was carried out for rapid assessment of morbidity and mortality due to vector borne diseases, entomological surveillance and preventive vector control measures taken by the health authority. Rapid assessment was carried out in the East, Central and North zones, which caters high risk areas and migrant population, of Ahmedabad city. House to house survey carried out in all the wards of 3 assigned zones for fever cases, deaths and breeding places of mosquito. Data was also collected from Urban Health Centre, Private clinics, trust hospitals and different laboratories in the wards. Epidemiological interpretation of various Entomological indices like House Index, Container Index and Breteau Index were done by WHO norms. Total 2800 houses and 14077 family members were surveyed. Total 5841 containers were checked. House index was 1.22%, 1.55% and 1.4%; Container index was 0.46%, 0.9% and 0.8%; Breteau index was 1%, 1.78% and 1.4% accordingly in three zones namely East, South & Central. Entomological indices were well controlled and in correlation with the fever cases in different areas of different zone and VBDs were also under control.