Найдено научных статей и публикаций: 1, для научной тематики: N-Acetylation
1.
Parshikov I. A., Freeman J. P., Lay J. O. Jr., Beger R. D., Williams A. J., Sutherland J. B.
- FEMS Microbiol. Lett. , 1999
A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus carried out the regioselective N-acetylation of ciprofloxacin to a single product, which was purified fro...
A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus carried out the regioselective N-acetylation of ciprofloxacin to a single product, which was purified from culture extracts by high-performance liquid chromatography. The metabolite was identified by mass and nuclear magnetic resonance spectrometry as 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-acetyl-1-piperazinyl)-3-quinolinecarboxylic acid.
FEMS Microbiology Letters. 1999. V.177. N 1. P.131–135.
