A single-stage innovative method of nano-sized hydroxyapatite Ca5(PO4)3OH (grain size equal 80 nm) synthetizing from aqueous solution was developed. This method is based on interaction between phosphoric acid solution and calcium nitrate in conditions, which are identical to conditions of hydroxyapatite formation in human organism. Structural and thermalphysic investigations of the compound were carried out using methods of high-temperature X-ray diffraction and differential scanning calorimetry. A big isomorphic capacity of apatite structure let us to suggest a number of chemical-modified hydroxyapatite creating ways. These modifications include such substitutions like “phosphorus-silicon”, “calcium-lanthanides”, “hydroxyl-fluorine”. Particularly hydroxyapatite doped by rare-earth elements can be used as an environmentally acceptable luminescent material. Isothermal batch reactor for a commercial production of hydroxyapatite was designed. Optimal conditions for the creating of hydroxyapatite-based bioceramic with controllable volume porosity were selected. Produced ceramic samples can be used in medical techniques for example in bone tissue engineering. Several steps of preclinical test were successfully passed. A new hybrid material which can be represented as high-porous hydroxyapatite ceramic impregnated with degradable polymer (chitosan) was obtained and its strength properties were investigated. For the first time the method of obtaining of hydroxyapatite whiskers (one-dimensioned dislocation-free crystals) using scheme “vapor-liquid-solid” was worked out. These whiskers can be used as a filling compound in composite materials. An improvement of hydroxyapatite sputtering on metallic and ceramic surfaces technique is also one of the most interesting areas of investigations.
Proceedings of the 2nd International Seminar on Chemistry. – 2011. – P. 47-50.

Compounds in Ca10(PO4)6Cl2–Pb10(PO4)6Cl2 system were synthesized by solid state reaction. It was ascertained using DTA and X-ray diffraction methods that in the investigated system there are two fields because of the formation a compound with formula Ca7Pb3(PO4)6Cl2. The first area is the Pb10(PO4)6Cl2–Ca7Pb3(PO4)6Cl2 which is characterized by unbounded mixing of components. The second Ca7Pb3(PO4)6Cl2–Ca10(PO4)6Cl2 area has complicated character due to presence of decomposition processes. In spite of the presence of the one nature polymorphic transitions of Ca10(PO4)6Cl2 and Pb10(PO4)6Cl2 the same effects on all solid solutions were not observed.
Thermochimica Acta. – 2011. – V. 526. – P. 72-77.

Compounds of composition Pb5(PO4)3FxCl1−x (0≤x≤1), which are synthetic analogues of minerals pyromorphite, flourapatite, and endlichite, were synthesized for the first time by high-temperature solid phase reactions. X-ray diffraction and IR spectroscopy were used to determine the structure of the compounds and revealed complete miscibility in the solid phase of the Pb5(PO4)3F–Pb5(PO4)3Cl binary system. Adiabatic reaction calorimetry was used to measure standard enthalpies of mixing and formation and show that the regular solutions model is applicable to the Pb5(PO4)3F–Pb5(PO4)3Cl system. Differential thermal analysis in tandem with high-temperature X-ray diffraction were used to study the phase diagram and characterize phase transitions.
Thermochimica Acta. – 2011. – V. 513. – P. 112-118.