Найдено научных статей и публикаций: 2, для научной тематики: Cytology
1.
Nesreen H. Hafez, Mohamed I. Fahim
- Russian Open Medical Journal , 2014
Background — The oral cavity can be home for a wide variety of lesions. To date, biopsy has remained the gold standard for diagnosing these lesions. Purpose — This study was carried out to assess the diagnostic accuracy of cytology in the oral lesions and to address the cytologic-histologic correlat...
Background — The oral cavity can be home for a wide variety of lesions. To date, biopsy has remained the gold standard for diagnosing these lesions. Purpose — This study was carried out to assess the diagnostic accuracy of cytology in the oral lesions and to address the cytologic-histologic correlation.
Patients and Methods — This prospective study included 72 patients with intraoral lesions. Fine needle aspiration cytology (FNAC) or scrap cytology was performed. The smears were immediately fixed in 95% alcohol for Papanicolaou staining. If there was sufficient material, cell block was prepared. When indicated immunocytochemical study was ordered. Final cytologic results were then compared with the definitive histopathological diagnoses which were considered the gold standard.
Results — Cytologically, 28 patients (38.9%) were diagnosed as benign/atypical and 44 (61.1%) as malignant/suspicious. The most common benign cytologic diagnosis was inflammation (42.9% of benign cases). The most common malignant cytologic diagnosis was squamous cell carcinoma (36.4%). Cytologic diagnoses were compared with histopathologic ones. There were 3 false negative cases and one false positive case. The sensitivity was 93.5%; specificity was 96.2%; positive predictive value (PPV) was 97.7%; negative predictive value (NPV) was 89.3% with a diagnostic accuracy of 94.4%. P-value was <0.001. Kappa was 0.882.
Conclusion — FNAC was found to be highly accurate in the diagnosis of oral lesions. Detailed cytomorphologic examination coupled with clinical data and appropriate immunocytochemical study, in some cases, can lead to an accurate diagnosis. Overlapping features of some tumors, especially in minor salivary gland, as well as limitation of sampling, were responsible for the inaccurate diagnoses.
Nesreen H. Hafez, Mohamed I. Fahim Diagnostic accuracy and pitfalls of fine needle aspiration cytology and scrape cytology in oral cavity lesions // Russian Open Medical Journal, Vol. 3, Issue 4, 2014, pp. 405-0
2.
Erokina N.L., Lepilin A.M., Zakharova N.B., Rogatina T.V., Lyapina Y.A., Prokofieva O.V., Lukashov V.A.
- Saratov Journal of Medical Scientific Research , 2011
The purpose of the study: rationale for selecting the method of immobilization of bone fragments of the mandible in patients with fractures, combined with chronic generalized periodontitis based on clinical and cytomorphological data. Materials and methods. Were examined 60 patients with mandibular ...
The purpose of the study: rationale for selecting the method of immobilization of bone fragments of the mandible in patients with fractures, combined with chronic generalized periodontitis based on clinical and cytomorphological data. Materials and methods. Were examined 60 patients with mandibular fractures in combination with chronic generalized periodontitis who underwent immobilization of the mandible in various ways. Patients underwent clinical examination and conventional cytomorphological examination of the contents of periodontal pockets. As a result, found that patients in the orthopedic treatment of the dynamics observed progression of inflammatory-destructive processes. When immobilization of the mandible with intermaxillary fixation titanium screws and the surgical method of treating inflammation at the level of periodontal pockets cropped. Conclusion. Given the smaller number of inflammatory complications of mandibular fractures in patients who have used the maxillary fixation screws in titanium, this is the best
Erokina N.L., Lepilin A.M., Zakharova N.B., Rogatina T.V., Lyapina Y.A., Prokofieva O.V., Lukashov V.A. The use of cytological studies of periodontal pockets of periodontitis patients with fractures of the mandible to select the method of immobilization // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 905-909