The article presents a historical overview of different measurement methods of mobility of middle ear structures. It points out a thorough research of transition from mechanical measurement techniques with mathematical approximation to the nanotechnological methods. The main approaches to modern mathematical models of middle ear construction including finite element method have been described in the work.
G.O. Mareev Modern mathematical models of middle ear (review) // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 1, 2012, pp. 95-100

Research is devoted to assessing the state of the middle ear structures by usage of modern nanotechnology methods. The history of the problem, various ancient and modern methods for studying the mobility of the middle ear structures have been described. The results of the research of eardrum movements by laser autodyne and their value in differential diagnosis of ear diseases have been presented. The research goal is to assess vibrations of middle ear structures by modern nanotechnological techniques. Materials: The study included 207 persons, divided into groups of healthy individuals and patients with sensorineural deafness, otosclerosis, adhesive otitis and tubootitis. Results: Exact frequency response vibration patterns of the middle ear and tympanic membrane have been obtained. Measurements have been made in open sound field in normal ears and ears with various pathology of middle and inner ear. The value of this method in differential diagnosis of ear diseases has been investigated. Conclusion: The use of laser autodyne for measuring middle ear structures vibration is a perspective and objective method of assessing auditory function. It is very necessary in modern otolaryngology for differential diagnosis of hearing pathology
Daykhes N.A., Mareev O.V., Mareev G.O., Usanov D.A., Skripal A.V. Application of laser autodyne for vibration assessment of tympanic membrane // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 894-897