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 Найдено научных статей и публикаций: 2, для научной тематики: fragment-based drug design


Связанные научные тематики:
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1.

In silico fragment-based drug design using PASS approach (публикация автора на scipeople)   

Filz O.A., Lagunin A.A., Filimonov D.A., Poroikov V.V. - SAR & QSAR Environ. Res. , 2012
Fragment-based drug design integrates different methods to create novel ligands using fragment libraries focused on the particular biological activities. Experimental approaches to fragment libraries preparation have some drawbacks caused by...
2.

Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino–5–aryliden–4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors (публикация автора на scipeople)     

Eleftheriou P., Geronikaki A., Hadjipavlou-Litina D., Vicini P., Filz O., Filimonov D., Poroikov V., Chaudhaery S.S., Roy K.K., Saxena A. - European Journal of Medicinal Chemistry , 2012
Balanced modulation of several targets is one of the current strategies for the treatment of multi-factorial diseases. Based on the knowledge of inflammation mechanisms, it was inferred that the balanced inhibition of...