The present article summarizes modern conceptions of tubulointerstitial fibrosis development mechanisms in children with vesicoureteral reflux. The review deals with the questions of extracellular matrix components accumulation and disintegration, tissue hypoxia, remodeling of blood flow, concentrat...
The present article summarizes modern conceptions of tubulointerstitial fibrosis development mechanisms in children with vesicoureteral reflux. The review deals with the questions of extracellular matrix components accumulation and disintegration, tissue hypoxia, remodeling of blood flow, concentration changes in inflammation, sclerosis and angiogenesis biomarkers in the progress of nephrosclerosis
Morozov D.A., Morrison V.V., Morozova O.L., Lakomova D.Y. Pathogenic basis and modern prospects in early diagnostics of nephrosclerosis in children with vesicoureteral reflux // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 151-157
