The article presents the results of monitoring of iodine intake and thyroid status in pregnant women in Saratov region according to the two cross-sectional studies in 1999 and 2008. The study involved 229 pregnant women. It has been established that there is a decrease in frequency of endemic goiter in pregnant women from 52,8 to 23,6% and increase in median urinary ioduria from 33,0 to 115,5 ug/l. However, iodine intake in pregnancy remains insufficient, as currently the median urinary ioduria is 150-249 ug/l (WHO, 2007). The frequency of maternal hypothyroxinemia, the most significant iodine deficiency disorders in pregnant women, has not changed in a 10-year period (1999 - 46,3%; in 2008 - 55,7%; p>0,1). The research has not obtained significant differences in the frequency of interrelated with pregnancy and delivery complications within two groups of patients
Naumova Yu.V. Monitoring of iodine intake and thyroid status of pregnant women in Saratov region from 1999 till 2008 // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 65-68

Comparison analysis of the state of newborns in the conditions of the absence of prenatal iodine prevention (group 1); irregular receiving inadequate preventive doses of iodine-containing drugs (group 2); adequate prenatal iodine prevention (group 3) has been carried out. It is shown that only an adequate consumption of iodine by pregnant women (at least 250 ug of potassium iodide per day) can significantly reduce the frequency of neonatal disorders of adaptation (in 2,3-2,5 times), disharmonious physical development (in 2,5-2,8 times), perinatal encephalopathy (in 1,5-1,7 times), acute infectious diseases (in 1,5-1,6 times) and neonatal hyperthyreotropinemia (in 4,2-9,4 times)
Kurmacheva N.A., Naumova Yu.V., Rogozhina I.E. State of newborns according to prenatal iodine intake // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 49-52

This article presents the data about the unsatisfactory quality of iodine prevention of pregnant women from Saratov region, about iodine poor consumption of mothers (ioduria median line 115,5 ug/l at recommended definitions 150-249 ug/l by the experts of World Health Organization) against inadequate low preventive dose of iodine medications, and about high frequency of maternal hypothyroxinemia (55,7%) and associated with it complications during pregnancy child bearing, defects of fetus condition and health of newborns. It was indicated that preventive acceptance of potassium iodine in dosage with 250 ug/day resulted in the decrease of absolute risk by 12-47% and in 2-8 times of ratio of complications during pregnancy and child bearing, damages of adaptation and diseases of the newborns
Naumova Yu.V., Kurmacheva N.A., Rogozhina I.E. Health state of pregnant women and newborns depending on quality of iodine prevention // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 3, 2010, pp. 535-540