For the purpose to determine the clinical pathogenetic efficacy of Cycloferon liniment in the combined therapy of parodontitis in patients with chronic brucellosis medical examination and treatment of 50 patients was carried out. It was established that use of liniment Cycloferon in the combined treatment of patients with pariodontitis against chronic brucellosis allowed to accelerate process of normalization of parameters of lipid peroxidation and antioxidant potential of blood, to decrease infection load (herpes symplex virus I, candida albicans, staphylococcus aureus) in parodontal recess and evidence of local inflammation with reduction of activity of tumour necrosis and interleukin 1b, that provided acceleration of recovery processes, lowering in frequency of pariodontitis recurrences
L.A. Soboleva, R.R. Syakin, N.V. Bulkina, A.A. Shuldyakov Оptimization of periodontitis treatment in patients with chronic brucellosis infection // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 2, 2010, pp. 403-405