The aim of the research is to study pharmacological properties and to determine safety effect diapason, toxico-logical properties of new adenine substances 9-[2-(4-isopropylphenopxy) aethyl] adenine under laboratory code VMA-99-82 which obtains antiviral activity in vitro. the results of the research of neurotoxicologic profile of combination of VMA-99-82 are presented in the work using technique of multistage testing according to «S.lrvin». while performing the research it has been established that safety level of substance VMA-99-82 refers to the class of low toxic combination. the diapason of doses (from 18,7 to 300 mg/kg) of substance evident therapeutic effect has been determined. Side-effects are not expressed significantly. therapeutic effect of the combination VMA-99-82 has behavioral reactions. thus the given substance must be further studied for psychotropic effect and its mechanism action
D.G. Kovalev, L.I. Bugaeva, A.A. Ozerov Weurotoxicologic profile of new adenine substances with antiviral activity // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 2, 2010, pp. 253-256