Найдено научных статей и публикаций: 1, для научной тематики: Antifungal activity.
1.
S.M. Roopan, N. Tamilselvan, F.R.Nawaz Khan
- Journal of Pharmacy Research , 2010
Isatin (1) underwent facile regioselective N-alkylation with various 2-chloro-3-chloromethylquinolines (2a-e) in the presence of KOt
Bu in THF at
70°C to afford corresponding N-alkylated derivatives (3a-e). Chemical structures of products were characterized using FTIR,
1H,
13C NMR and
Mass sp...
Isatin (1) underwent facile regioselective N-alkylation with various 2-chloro-3-chloromethylquinolines (2a-e) in the presence of KOt
Bu in THF at
70°C to afford corresponding N-alkylated derivatives (3a-e). Chemical structures of products were characterized using FTIR,
1H,
13C NMR and
Mass spectral studies. All the title compounds were screened for antimicrobial studies. Most of the tested compounds exhibited potent in vitro
antimicrobial activity dose dependently.