Creating conditions in order to overcome negative consequences of downturn in the real economic sector, update industry and develop more prosperous competitive agglomerations is proved to be an extremely urgent problem for the most Russian Federation regions. Applying cluster approach in organizational policy implemented by regional authorities is one of possible means to solve problems referred above. Supporting sustainable development and strong economic growth using innovative methods of regional competitiveness is one of the prerequisite to form industrial complexes based on cluster technologies. Both traditional and new propulsion industries could serve as a base for formation of industrial complexes. Activization of processes mentioned above results in formation of the investment and innovative systems in regions, reduction of terms connected with adoption of innovations into production, more efficient usage of the recourse potential of a region, different forms of the public-private partnership.