The research goal was to estimate efficiency of medicine phosphogliv by the directed administration in complex therapy for patients with biliary pancreatitis and НСV- infection. 62 patients with biliary pancreatitis and НСV-infection were examined. These patients were divided into 2 comparable groups: control group I (50 persons) and basic group II (12 persons). In group I traditional basic therapy of biliary pancreatitis was carried out with injection of phosphogliv intravenously. Patients of group II were given erythrocytes intravenously with average therapeutic dose of phosphogliv. Introduction of medicines in autologous erythrocytes was performed by hypotonic lysis. Effective influence of directed administration of preparation phosphogliv demonstrated decrease in level of bilirubin in blood, activity of AlAt, AsAt in patients of research group. Side-effects were not revealed. In conclusion the investigation proved that more effective influence of phosphogliv on level of bilirubin in blood and activity of AlAt, AsAt can be reached in combination with traditional basic therapy.
Alexei L. Charyshkin, O.V. Midlenko, V.I. Midlenko, Alexandr L. Charyshkin Directed administration of medicines in complex treatment of patients with biliary pancreatitis and нсv-infection // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 1, 2010, pp. 81-84