Objective of the study is to prevent bleeding from papillosphincterotomic wounds after endoscopic intervention. Methods: Analysis of the results of endoscopic intervention of patients receiving treatment at the Saratov regional hospital during the period from 2006 to 2010. Endoscopic papillotomy and papillosphincterotomy have been performed in 250 patients. Bleeding has been occurred in 21 (8.4%) of cases. Results: Bleeding from the PST or PT — wounds has occurred in self-discharge of CBD stones into duodenum. Conclusion: According to the observations, method of prevention of bleeding from PST-wound in choledocholithiasis has been proposed. It deals with the temporary installation of stent in the distal part of common bile duct for 2-4 days in multistage endoscopic operations.
TolstokorovA. S., Sarkisyan Z. О., Goch Е.М., Skopets S. М., Dergunova S. A., Rakhnayev D. Y. Parab D. Профилактика кровотечения из папиллосфинктеротомической раны после эндоскопических вмешательств на большом дуоденальном сосочке при холедохолитиазе // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 4, 2012, pp. 1012-1016

Objective of the study: Prevention of acute pancreatitis after diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). Material and Methods. Analysis of the results of diagnostic and therapeutic ERCP, of the patients treated at Saratov Regional clinical hospital f during the period from 2006 to 2010. Results, lincrease in pancreatic amylase levels in blood above 50 U/l till ERCP is a risk factor for development of acute pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). Conclusion. The above-stated follows to the background of increased pancreatic amylase levels in blood, performance of endoscopic retrograde cholangiopancreatography led to the development of acute pancreatitis.
Tolstokorov A.S., Sarkisyan Z.О., Goch Е.М., Volchkov A.S., Skopets S.М., Dergunova S.A., Rakhnayev D.Ya. Method of prevention of acute pancreatitis after diagnostic and therapeutic endoscopic retrograde cholangiopancreatography // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 3, 2012, pp. 845-849

Objective of the study: determination of the degree of influence of bilirubin in the blood during obstructive jaundice, on blood clotting. Methods. A retrospective study of case histories of patients with obstructive jaundice who have been treated at the Regional Hospital of Saratov in the period from 2000 to 2010. Results. The results confirm the assumption that the causes of bleeding in obstructive jaundice is hepatic failure. Conclusion. Absence of bile in the small intestine in obstructive jaundice is not the cause of bleeding. Bile acids are not involved in metabolizing fat-soluble vitamin K1
Tolstokorov A.S, Sarkisian Z.O. Effect of hyperbilirubunemia on coagulation system of blood in patients with obstructive jaundice // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 2, 2012, pp. 329-332

The article deals with the contemporary data on etiology and pathogenesis of cholelithiasis, the stages of biliary pathology (motorotonic disturbances of gallbladder and sphincteric apparatus of anhepatic biliary tracts — chronic acalculous cholecystitis — cholelithiasis). The factors, affecting the gallbladder stones formation are described. The problems of pathogenesis of gallbladder cholesterosis are reviewed. The authors come out with an assumption, that disturbances in cholesterol metabolism in the human body play the leading role in the development of this disease.
N.V. Yekimova, V.B. Lifshits, V.G. Sub-botina, N.Yu. Papshitskaya, L.S. Sulkovskaya Etiopathogenesis of Cholelithiasis and gallbladder cholesterosis // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 3, 2009, pp. 337-341

The analysis of treatment of 67 patients with gall-stone disease complicated by choledocholithiasis and distal section stenosis of the common bile duct during the period from 2002 till 2007 is presented in the article. This group of patients took part in a research study of the single-stage method of treatment with laparoscopy has been preferably performed in this group of patients. The laparoscopy treatment techniques have been proved to be highly effective
S.N. Perekhodov, О .A. Dolgov, P.N. Vanjushin, K.Yu. Grigorjev ENDOSURGICAL TREATMENT OF GALL-STONE DISEASE COMPLICATED BY CHOLEDOCHOLITHIASISAND DISTAL STRUCTURE OF COMMON BILE DUCT // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 4, 2008, pp. 101-104