The aim of the article is to study the relation of chronic heart failure, cognitive disturbances and changes in white matter of brain. Material et methods: Cognitive tests, echocardiography, MRI of brain and measurement of NT-proBNP in venous blood have been performed in 57 patients with l-IV functional class of chronic heart failure. Program STATISTICA 7 (methods of nonparametric correlation analysis) has been used to assess the results. Results: It has been established that during the increase of severity of CHF decrease in the thickness of medium-sized peduncles of cerebellum and the changes of coefficients of diffusion of water molecules in white matter have been marked. Conclusions: On the basis of these findings it has been determined that CHF is an independent cause of micromorphological brain damage and later the progressive atrophy of white matter. It clearly shows that the cerebral changes cause cognitive dysfunction.
Shvarts Y.G., Akimova N.S., Martynovich Т.V. Analysis of changes in white matter of brain and cognitive disturbances in patients with chronic heart failure and ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 1, 2013, pp. 78-82

The questions of diagnostics and classification of cognitive disturbances in 112 patients with hypertensive encephalopathy are considered. The diagnosis of cognitive frustration was based on results of expanded neuropsychological examination with a qualitative and quantitative estimation of the received results. 56 % of the examined patients had the moderate cognitive disturbance syndrome. Neurodinamical-disregulation and primary-dismnestical types have been revealed. Taking into account, that opportunities of treatment and rehabilitation of patients with dementia noware rather limited, the study of predementical forms of cognitive disturbances when therapeutic actions are considered to be the most effective and of great importance.
I.E. Poverennova, E.V. Sevastyanova FEATURES OF COGNITIVE DISTURBANCES AT THE ARTERIAL HYPERTENSIA // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 1, 2008, pp. 88-92