Purpose: assessment the heavy psychosomatic and all-somatic cardiovascular and cerebrovascular pathology of patient, transferred an acute I degree radiation sickness, from the general evenly gamma-beta radiation. Conclusions. The subdepressive and disturbing-depressive syndrome of patient, transferred an acute radiation sickness (ARS) of I degree, from the general evenly gamma-beta radiation, was independent risk factor of development of multifocal atherosclerosis; Features of development of all-somatic and psychosomatic pathology of patient are based on a combination of genetic prerequisites, environment influences (the stress caused by accident on the ChNPP) and social factors, influencing on him during a course of life, especially during early socialization. Thus at development of psychosomatic frustration the combination of feature of the mental reaction connected with the personal characteristic and special relationship between mental (stress) and physiological (somatic) by aspects of reaction which led to metabolism violation, to aging, decrease in adaptation opportunities of an organism and development age — dependent pathology took place.
Metlyaeva N.A., Lartsev M.A., Shcherbatykh O.V., Bushmanov A.Yu., Krasnyuk V.I. Multifocal atherosclerosis in patient after acute first degree radiation sickness. // Saratov Journal of Medical Scientific Research, Vol. 10, Issue 4, 2014, pp. 862-867

The aim of the article is to study the relation of chronic heart failure, cognitive disturbances and changes in white matter of brain. Material et methods: Cognitive tests, echocardiography, MRI of brain and measurement of NT-proBNP in venous blood have been performed in 57 patients with l-IV functional class of chronic heart failure. Program STATISTICA 7 (methods of nonparametric correlation analysis) has been used to assess the results. Results: It has been established that during the increase of severity of CHF decrease in the thickness of medium-sized peduncles of cerebellum and the changes of coefficients of diffusion of water molecules in white matter have been marked. Conclusions: On the basis of these findings it has been determined that CHF is an independent cause of micromorphological brain damage and later the progressive atrophy of white matter. It clearly shows that the cerebral changes cause cognitive dysfunction.
Shvarts Y.G., Akimova N.S., Martynovich Т.V. Analysis of changes in white matter of brain and cognitive disturbances in patients with chronic heart failure and ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 1, 2013, pp. 78-82

The article considers quality of life as an evaluation category of state of a subject in conditions of illness. The results of the research of quality of life relevant to health in patients with coronary heart disease are given in the work. Quality of life defined on the basis of the questionnaire of WHOQOL-100 supplementing an illness picture is a multiple-factor criterion in condition assessment of such category of patients.
Baleva Е.S., Khrom I.L., Aleshkina O.Yu. Quality of life evaluation relevant to health in patients with coronary heart disease // Saratov Journal of Medical Scientific Research, Vol. 9, Issue 1, 2013, pp. 145-147

Purpose: the study of interrelation between characteristics of psychological profile of elderly patients, level of stress hormones in blood serum and character of IHD course. Materials and Methods. The level of catecholamines and cortisol in blood was investigated in two groups of elderly patients (379 patients) formed according to their psychological profile with the help of Cattell questionnaire. Multispiral coronarography was conducted in patients suffering IHD. Results. The established differences of stress level correlated with the characteristics of the course of IHD at all the examined patients. In spite of various levels and reactions of adaptive hormones on stress situations the prevalence of IHD appeared to be the same in both groups although manifestation and clinical severity of coronary insufficiency varied in patients of different groups. The number of patients suffered myocardial infarction, among them with Q-wave, occurred to be higher in one of the groups despite the fact that changes in their coronary arteries were less expressed. Conclusion. The character of psychological profile causes different stress resistance of patients and leads to various levels of stress hormones in blood serum. Depression can become a marker of severe course of cardiovascular pathology. The character of psychological profile influences the course of IHD.
Prokhorenko I.О., Zarubina Е.G. Influence of personality characteristics on spectrum of catecholamines and course of ischemic heart disease in elderly patients // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 4, 2012, pp. 942-946

The review presents the features of modern viewpoints on the theory of atherosclerosis pathogenesis. The possibilities of mathematical modelling of hemodynamics in coronary arteries in consideration of their morphological parameters and relationship with myocardium are described
Chelnokova N.O., Golyadkina A.A., Schuchkina O.A. Clinicopathologic basis of hemodynamics modelling in the system of coronary arteries in consideration of its interaction with myocardium (review) // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 762-768

Anemic syndrome of different severity often accompanies ischemic heart disease (IHD) and chronic heart failure (CHF). Anemia has association with unfavorable prognosis in patients with all forms of CVD — acute and chronic. In this article the authors summarize a literature review of English articles dedicated to the problem of anemia and ischemic heart disease (IHD) and the results of original research on the relationship between anemic syndrome and prognosis in the hospitalized patients with IHD and chronic heart failure (CHF). Anemia is frequently observed in patients with CHF, and evidence suggests that anemia might be associated with an increased mortality in both systolic and diastolic chronic heart failure (CHF), morbidity and rate of hospitalization in CHF patients. Moreover, CHF itself could be involved in the pathogenesis of anemia. Early studies suggested a pathogenic role of inflammation mediators. The normalization of hemoglobin concentration by EPO and iron supply in patients with CHF and chronic renal insufficiency results in improved exercise capacity by increasing oxygen delivery and improving cardiac function. However, there is limited information concerning the association of hemoglobin concentration and new onset of clinically recognized coronary artery disease, and lack of information about the effect of anemia treatment on prognosis of acute forms of IHD
Kaluta Т.Yu., Suvorova S.A., Shvarts Y.G. Anemic syndrome in patients with ischemic heart disease and chronic heart failure (review) // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 4, 2011, pp. 831-837

158 patients with ischemic heart disease (IHD) have been understudy during the period of 12 months in out-patient conditions. After completion of the primary examination all the patients of basic group (118 patients) received clinical way method of treatment. Patients of the comparison group (40 patients) after provided treatment were cared by their local therapeutists (cardiologists). The findings proved the fact that treatment of patients after cardiosurgery by clinical way method in out-patient conditions enabled to raise patient motivation to treatment, thereby assisting them to feel better, promoting normalization of arterial pressure data. The research results stated that clinical way method of treatment may be considered as rational and effective
Vardosanidze S.L., Galstyan A.S. Clinical way method in treatment of out-patients with ischemic heart disease after cardiosurgery // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 4, 2010, pp. 824-828

The article presents the results of studies of life quality of patients with ischemic heart disease and old myocardial infarction. The life quality is considered as an independent and objective multifactor indicator reflecting the status of this category of patients
D.A. Osipov, T.V. Rozhdestvenskaya, I.L. Krom, А.Р. Rebrov Objective evaluation of life quality of patients with ischemic heart disease // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 3, 2010, pp. 585-588

The article presents the research results on the correlation between anemic syndrome and main risk factors in hospitalized patients with different forms of cardiovascular pathologies. This category of patients is characterized by more severe arterial hypertension and low level of total cholesterol in blood. It has been revealed that anemia in patients with CVD (cardiovascular diseases) is not only associated with unfavorable prognosis, but also becomes a marker of peculiarities in mechanism of disease development indicating the severity of inflammatory component
Suvorova S.A., Parkhonyuk Е.М., Shvarts Yu.G. Anemic syndrome in hospitalized patients with ischemic heart disease: inflammation marker or factor of pathogenesis? // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 3, 2010, pp. 596-600

The article is devoted to some aspects of influence of digestive apparatus diseases (chronic gastritis, a stomach ulcer, chronic cholecystitis) on clinical course ofischemic heart disease. It is revealed, thatthe patients with clinical symptomatology are typically to have extra cardiac hue of painful heart attacks. The patients with influence ofischemic heartdisease and digestive apparatus disorders have sympathetic overbalance of the vegetative one against the background of the parasympathotonia.
E.U. Eremina, E.V. Shipalkina SOME ASPECTS OF INFLUENCE OF DIGESTIVE ORGANS DISEASES ON CLINICAL COURSE OF ISCHEMIC HEART DISEASE // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 1, 2008, pp. 122-127