The central part of brain infarction (Bl) pathogenesis is hemostatic blood activation. Aim: to study platelet aggregative ability in dynamics of acute Bl at the marked stenosis of cerebral arteries (>50%). Materials and methods. Investigation included 39 patients at acute Bl with average age 73,9±8,3 years. Control group consisted of 18 healthy persons with average age 60,2±6,8 years. Evaluation of platelet aggregation was performed with application of light-transmission aggregometer «SOLAR» (RB) and aggregation inductors — solutions of adenosine diphosphate with concentration of 0,5 и 2,0 umol/l and collagen of 2,0mg/ml concentration. Results. Significant hyperaggregation platelet reaction on the 1 st and 10th days of hospitalization without positive changes under treatment has been revealed. Conclusion. Thus, obtained results prove the necessity of monitoring of individual patients sensitivity to antiplatelet therapy in secondary prevention of ischemic stroke with optical aggregometry and inductors complex.
Stepanova Yu.l., Gontchar I.A., Likchachev S.A. Characteristics of platelet aggregative ability at patients with brain infarction and marked stenosis of cerebral arteries // Saratov Journal of Medical Scientific Research, Vol. 8, Issue 3, 2012, pp. 770-774

150 cadets ages 16 to 25years were under the obsrevation of adaptation of intravascular microcirculation component during the course of their military professional study. The research data proved that active erythrocyte aggregation, the size of thrombocyte aggregates and the speed of thrombocyte aggregation are higher in the first-, second- and third-year cadets than in senior students. These findings are to be used in the assessment ofcadets' adaptation to the military service and the prognosis of their professional capacity.
V.F. Kirichuk, A.P. Shmatov ADAPTATION OF MICROCIRCULATION INTRAVASCULAR COMPONENT IN CADETS DURING THE COURSE OF THEIR MILITARY PROFESSIONAL STUDY // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 4, 2008, pp. 22-26