Diagnostic significance of quantitative measurement of muscle acetylcholine receptor (AChR) antibodies by ELISA in patients with myasthenia was shown. Blood serum analysis of 111 patients (30 in dynamics for various treatment types) was carried out. The most essential elevation of antibodies quantity was observed in patients with generalized myasthenia type. After thymectomy it was significantly reduced. Quantitative antibodies measurement by interaction with AChR domen in ELISA is supposed to be used as additional diagnostic method of autoimmune myasthenia
Zh Nevrol Psikhiatr Im S S Korsakova. 2003;103(2):34-7. Russian.