Найдено научных статей и публикаций: 45, для научной тематики: -
41.
D.A.Gusarov, V.D.Gusarova, A.V.Mikhalev, V.A.Lasman, D.I.Bairamashvili, A.F.Mironov, N.K.Senatorova, A.V.Senatorov
- Russian Journal of Bioorganic Chemistry. 2009. V.35. No 1. P.47-53. , 2009
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Russian Journal of Bioorganic Chemistry. 2009. V.35. No 1. P.47-53.
42.
6. D.Gusarov, V.Nekipelova, V.Gusarova, V.Lasman, D.Bairamashvili
- Journal of Chromatography B. 2009. V.877. P.1216-1220. , 2009
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Journal of Chromatography B. 2009. V.877. P.1216-1220.
43.
D.A.Gusarov, V.D.Gusarova, A.F.Mironov, D.I.Bairamashvili
- Russian Journal of Biopharmaceuticals. 2009. V.1. No.1. P.3-11. , 2009
In spite of the fact that diabetes mellitus has been described at the X century, the recovery of this disease previously being mortal one yet is not impossible. Patient suffered from diabetes mellitus needs continuous insulin administration during a day. In recent years a number of studies held in t...
In spite of the fact that diabetes mellitus has been described at the X century, the recovery of this disease previously being mortal one yet is not impossible. Patient suffered from diabetes mellitus needs continuous insulin administration during a day. In recent years a number of studies held in the world as well as in Russia allowed to improve the quality of patient’s life by means of investigation of novel pharmaceutical dosage forms of insulin and new insulin analogs which have led to a better control of glucose level. The present paper describes modern tendencies in the field of long-acting insulins.
Russian Journal of Biopharmaceuticals. 2009. V.1. No.1. P.3-11.
44.
K.O.Sochilina, V.O.Nekipelova, D.A.Gusarov
- Russian Journal of Biopharmaceuticals. 2009. V.1. No.1. P.23-26. , 2009
The novel, domestically produced hydrophilic gel for size-exclusion chromatography has been developed. It was shown that the pointed gel being nearly the same to the sephadex G-75 by their operating characteristics however lacks some of the disadvantages of the latter. Namely, the developed gel is s...
The novel, domestically produced hydrophilic gel for size-exclusion chromatography has been developed. It was shown that the pointed gel being nearly the same to the sephadex G-75 by their operating characteristics however lacks some of the disadvantages of the latter. Namely, the developed gel is stable at high pressure and at low or high pH and is liable to biodegradation. The synthesized sorbent allows to perform proteins group separation as well as fractionation and desalting.
Russian Journal of Biopharmaceuticals. 2009. V.1. No.1. P.23-26.
45.
V.D.Gusarova, D.A.Gusarov, E.N.Shepel, A.V.Mikhalev, V.A.Lasman
- Russian Journal of Biopharmaceuticals , 2009
The hydrolysis of recombinant preproinsulin yields the human insulin as a main product and also B30-desthreonine insulin as one of the by-products. Since physicochemical properties of human genetic insulin and B30-desthreonine insulin are similar its chromatographic behavior is also nearly the same....
The hydrolysis of recombinant preproinsulin yields the human insulin as a main product and also B30-desthreonine insulin as one of the by-products. Since physicochemical properties of human genetic insulin and B30-desthreonine insulin are similar its chromatographic behavior is also nearly the same. That is why it is complicated to determine analytically the percentage of B30-desthreonine insulin in insulin-containing solutions. In the given study the development of the analytical quantitation of B30-desthreonine insulin by means of HPLC was described.
Russian Journal of Biopharmaceuticals. 2009. V.1. No.1. P.28-33.