Objective. The research goal is to estimate prognostic and diagnostic possibilities of markers of endothelial dysfunction, deciduation, apoptosis and cellular proliferation concerning realization of placental insufficiency. Material. 154 women of high risk group of severe placental insufficiency development have been examined in dynamics of the second and third trimesters of pregnancy. 30 healthy pregnant women have made the control group. Research methods are clinical, immunological, instrumental. Results. It is established that prognosis and early diagnostics for severe placental insufficiency can be carried out with application of monitoring of the maintenance of endothelial dysfunction markers, placental fibers of a mother placenta membrane, apoptosis and cellular proliferation in blood. In the second trimester of pregnancy prognostically significant criteria have included an increase of an index of cytotoxicity of antien-dothelial antibodies, the general IgE, lymphocytes, expressing Fas/APO-1/CD 95-receptor, TNFb and decrease of FGP. Conclusion. Therefore the forms of realization and severity level of placental insufficiency have been caused by the beginning and degree of damages in adaptation of endothelial systems, activation of the immunopathological reactions in the placenta manifested by trophoblastoma programmed cellular destruction of lymphocytes
Lipatov I.S., Tezikov Yu.V. Prognosis and diagnostics for placental insufficiency according to markers of endothe-lial dysfunction, deciduation, apoptosis and cellular proliferation // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 1, 2011, pp. 52-59

Gestational diabetes is defined as a violation of carbohydrate metabolism resulting in hyperglycemia of varying severity, firstly revealed or developed during the pregnancy. The article presents current data on the occurrence, etiology and pathogenesis of gestational diabetes, as well as methods for screening and diagnostics of disorders of carbohydrate metabolism during pregnancy. It explains the basic principles of diet therapy
Kostenko I.V., Rogozhina I.E., Sukhankina G.V., Ryzhkina S.A. Gestational diabetes mellitus: risk factors development, occurrence, diagnostics and treatment (review) // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 2, 2011, pp. 534-541

The literature review presents the specificity of diagnostic aid given to patients of reanimation departments. It points out the most common difficulties that physicians face in such conditions
Sadchikov D.V., Prigorodov М.V., Ivanov R.V. Diagnostic specificity in reanimation (review) // Saratov Journal of Medical Scientific Research, Vol. 7, Issue 2, 2011, pp. 404-409

The description of investigation of predisposition to potential danger of collapse complications at 429 first-year students during physical training is presented using the analysis of pulse wave form. With the help of developed device the group of students with predisposition to risk of collapse complications during physical activity has been revealed. The results of clinical examination have confirmed the predisposition of the given group to risk of collapse complications
Usanov D.A., Protopopov А.А., Skripal A.M, Averyanov A.P., Repin V.F., Rytik A.P., Vagarin A.Yu., Kuznetsov M.A., Petrova M.G. Diagnostics of evolution of risk collapse complications at student group with anomalous cardiovascular reaction // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 3, 2010, pp. 615-619

В статье исследуются вопросы диагностирования лопаток авиадвигателей в процессе эксплуатации на основе наборов значений спектров затухающих колебаний лопаток после ударного возбуждения. В ходе проведенных экспериментов предложен новый оператор мутации. // The article investigates issues of diagnosing blades of aircraft engines in operation basing on values sets of the spectra of damped oscillations of the blades after the shock excitation. In the series of the experiments a new mutation operator was suggested.

На примере монокристаллов Si(As,P,B) и GaSb(Si) показаны возможности рентгенодифракционной диагностики сильнолегированных кристаллов полупроводников в отношении характеризации состояния примеси – находится ли она в виде твердого раствора или на разных стадиях его распада. Найдено оптимальное сочетание методов для получения информации о микросегрегации и структурной неоднородности в кристаллах со слабым и сильным поглощением рентгеновских лучей. Основой являются более чувствительные, чем традиционно используемые методы рентгеновской дифракционной топографии и дифрактометрии. // Using Si(As, P, B) and GaSb(Si) single crystals the possibilities of X-ray diffraction techniques for diagnostics of heavily doped semiconductor crystals in characterization of impurity state – whether it is in the crystals in the form of solid solution or under various stages of its decomposition - are shown. The best combination of techniques for receiving information about the microsegregation and structural inhomogeneity in the crystals with slight and strong absorption of X-rays has been found. The more sensitive methods of X-ray diffraction topography and diffractometry than traditionally used ones form a basis for this combination.

Alcoholic polyneuropathy is one of the most important challenges of health care not only in Russia, but throughout the world. The problems concerning pathogenesis, clinical manifestations, diagnosis and treatment of the above clinical form of alcoholic polyneuropathy are discussed
D.N. Beloglazov, V.G. Lim, A.A. Svistunov Alcoholic polyneuropathy // Saratov Journal of Medical Scientific Research, Vol. 6, Issue 1, 2010, pp. 117-120

Dynamics inspection of pregnant women with gestosis, including analysis of biochemical parameters is carried out. Change of metabolic concentration and activity of enzymes in blood serum depending on gestosis course is revealed. Opportunities of estimation of the given parameters for early gestosis diagnostics are determined.
N.R. Ermakova DYNAMICS OF BIOCHEMICAL PARAMETERS OF BLOOD SERUM AT GESTOSIS // Saratov Journal of Medical Scientific Research, Vol. 5, Issue 1, 2009, pp. 54-56

The article reflects modern literary data about approaches to diagnostics, forecasting of current and treatment of a climacteric syndrome at women.
N.V.Dyo, G.I.Khripunova MODERN APPROACHES TO DIAGNOSTICS, FORECASTING OF CURRENT AND TREATMENT OF CLIMACTERIC SYNDROME AT WOMEN // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 3, 2008, pp. 125-130

Questions of occurrence of cervical dizziness at 190 patients with cervical osteochondrosis, anomalies ofcraniovertebral transition and "switch" trauma of a cervical partof the backbone are discussed. On the basis of the results of complex examination with use of ultrasonic and neurovisualization techniques pathogenetic mechanisms of the developmentof cervical dizziness are discussed.
N.A. Deputatova, I.E. Poverennova, O.V. Zelentsova CLINICAL-DIAGNOSTIC AND PATHOGENETIC ASPECTS OF CERVICAL DIZZINESS // Saratov Journal of Medical Scientific Research, Vol. 4, Issue 2, 2008, pp. 90-94